C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: mucosa associated lymphoid tissue lymphoma translocation gene 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000172175 MALT1 9606 + 18:58671386-58750139 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000345724 MALT1-002 58671532-58748154 protein_coding
  ENST00000348428 MALT1-001 58671386-58750139 protein_coding
  ENST00000587438 MALT1-005 58741431-58745792 retained_intron
  ENST00000589873 MALT1-003 58733510-58748031 retained_intron
  ENST00000591792 MALT1-004 58672207-58700586 protein_coding

Homo sapiens EnsemblGRCh38

Genome
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Genes
Gene structures from Ensembl
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Transcripts
Structures from Ensembl
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Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000345724ENST00000348428
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000345724 1.206±0.00 N/A 0.683±0.00 0.458±0.04 1.857±1.09 0.736±0.00 0.518±0.00 1.074±0.00 4.217±0.00 2.315±0.86 0.845±0.00 3.421±1.28 1.043±0.60 9.998±5.80
ENST00000348428 1.343±0.00 2.811±0.00 N/A 0.914±0.00 1.039±0.08 1.561±0.16 1.625±0.63 2.060±0.00 0.694±0.00 N/A 0.597±0.00 1.639±0.81 1.203±0.34 5.351±2.22

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0006OD CIL_0006OD_0001 CGP 18:58481247-58750139
CIL_00086L CIL_00086L_0001 VISTA 18:58504415-59107634
CIL_0006O5 CIL_0006O5_0001 CGP 18:58671386-58986480

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001923 IEA B-1 B cell differentiation
GO:0002020 IEA protease binding
GO:0002237 IEA response to molecule of bacterial origin
GO:0002726 IMP positive regulation of T cell cytokine production
GO:0004197 NAS:IEA cysteine-type endopeptidase activity
GO:0004842 IDA ubiquitin-protein transferase activity
GO:0004871 IMP signal transducer activity
GO:0005515 IPI:IEA protein binding
GO:0005634 IDA nucleus
GO:0005730 IDA nucleolus
GO:0005737 IDA cytoplasm
GO:0005829 TAS cytosol
GO:0005886 TAS plasma membrane
GO:0006508 IDA:IEA proteolysis
GO:0006952 NAS defense response
GO:0007250 IMP activation of NF-kappaB-inducing kinase activity
GO:0008233 IDA peptidase activity
GO:0009620 IEA response to fungus
GO:0016567 IDA protein ubiquitination
GO:0019209 IMP kinase activator activity
GO:0031398 NAS positive regulation of protein ubiquitination
GO:0032449 NAS CBM complex
GO:0032743 IMP positive regulation of interleukin-2 production
GO:0038095 TAS Fc-epsilon receptor signaling pathway
GO:0042098 IEA T cell proliferation
GO:0042113 IEA B cell activation
GO:0042981 IDA regulation of apoptotic process
GO:0043066 NAS negative regulation of apoptotic process
GO:0043123 IMP positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0043234 IDA protein complex
GO:0043621 IPI protein self-association
GO:0045087 TAS innate immune response
GO:0050852 IDA T cell receptor signaling pathway
GO:0050856 IEA regulation of T cell receptor signaling pathway
GO:0050870 IC positive regulation of T cell activation
GO:0051092 IMP positive regulation of NF-kappaB transcription factor activity
GO:0051168 IDA nuclear export
GO:0051259 IDA protein oligomerization

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000077768 malt1b mucosa associated lymphoid tissue lymphoma translocation gene 1b protein_coding Danio_rerio
ENSMUSG00000032688 Malt1 mucosa associated lymphoid tissue lymphoma translocation gene 1 protein_coding Mus_musculus

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