C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: chemokine (C motif) receptor 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000173578 XCR1 9606 - 3:46017024-46027742 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000309285 XCR1-001 46017024-46027742 protein_coding
  ENST00000395946 XCR1-002 46021840-46027487 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000309285ENST00000395946
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000309285 0.029±0.00 0.199±0.00 0.013±0.00 0.038±0.00 0.129±0.03 0.010±0.00 0.054±0.00 0.050±0.00 0.134±0.10 0.196±0.02 0.012±0.00 0.096±0.05 2.757±1.57 0.015±0.00
ENST00000395946 N/A N/A N/A 0.138±0.00 N/A 0.058±0.00 N/A N/A N/A N/A N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0003OL CIL_0003OL_0001 CGP 3:45940933-46027742

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004930 IEA G-protein coupled receptor activity
GO:0004950 IEA chemokine receptor activity
GO:0005886 TAS plasma membrane
GO:0005887 TAS integral component of plasma membrane
GO:0006935 IEA chemotaxis
GO:0006954 TAS inflammatory response
GO:0007186 TAS:IEA G-protein coupled receptor signaling pathway
GO:0007187 TAS G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger
GO:0007204 TAS positive regulation of cytosolic calcium ion concentration
GO:0016021 IEA integral component of membrane
GO:0034097 IEA response to cytokine
GO:0051209 IEA release of sequestered calcium ion into cytosol
GO:0070098 IEA chemokine-mediated signaling pathway

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000052988 XCR1 (1 of 4) chemokine (C motif) receptor 1 protein_coding Danio_rerio
ENSDARG00000054846 XCR1 (2 of 4) chemokine (C motif) receptor 1 protein_coding Danio_rerio
ENSDARG00000054847 xcr1a chemokine (C motif) receptor 1 protein_coding Danio_rerio
ENSDARG00000087978 XCR1 (4 of 4) chemokine (C motif) receptor 1 protein_coding Danio_rerio
ENSMUSG00000060509 Xcr1 chemokine (C motif) receptor 1 protein_coding Mus_musculus

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