C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: exonuclease 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000174371 EXO1 9606 + 1:241847967-241895148 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000348581 EXO1-201 241848731-241889937 protein_coding
  ENST00000366548 EXO1-001 241848180-241889939 protein_coding
  ENST00000423131 EXO1-004 241848225-241858589 protein_coding
  ENST00000437497 EXO1-005 241848950-241858589 protein_coding
  ENST00000450748 EXO1-003 241848951-241853481 protein_coding
  ENST00000469419 EXO1-006 241850492-241860704 processed_transcript
  ENST00000493702 EXO1-007 241848983-241858718 processed_transcript
  ENST00000518483 EXO1-002 241848831-241889746 protein_coding
  ENST00000518741 EXO1-010 241885357-241895148 processed_transcript
  ENST00000519225 EXO1-008 241847967-241850460 protein_coding
  ENST00000521202 EXO1-011 241879040-241889594 protein_coding
  ENST00000523590 EXO1-009 241848251-241853481 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungOvaryPlacentaTestisENST00000348581ENST00000366548ENST00000423131ENST00000437497ENST00000469419ENST00000518483ENST00000518741ENST00000519225ENST00000521202
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Ovary Placenta Testis
ENST00000348581 0.029±0.00 N/A N/A N/A N/A 0.269±0.00 0.023±0.00 0.074±0.00 N/A N/A 0.928±0.00 N/A N/A
ENST00000366548 N/A 0.031±0.00 N/A 0.020±0.00 0.401±0.00 N/A N/A N/A N/A N/A 0.450±0.15 0.788±0.55 0.648±0.00
ENST00000423131 N/A N/A N/A N/A N/A 1.219±0.00 N/A N/A N/A 0.797±0.00 1.642±0.00 N/A N/A
ENST00000437497 N/A N/A N/A N/A N/A N/A 0.109±0.00 N/A N/A N/A N/A N/A N/A
ENST00000469419 N/A 0.246±0.00 0.421±0.00 0.061±0.00 0.078±0.00 N/A N/A N/A 0.392±0.00 N/A N/A N/A N/A
ENST00000518483 N/A 0.124±0.00 N/A 0.051±0.00 0.281±0.21 0.280±0.17 0.043±0.00 0.191±0.00 0.004±0.00 0.114±0.00 0.232±0.18 0.370±0.08 1.087±0.53
ENST00000518741 0.170±0.00 0.491±0.00 N/A N/A 0.271±0.00 N/A N/A 0.209±0.00 0.106±0.00 0.237±0.00 N/A N/A N/A
ENST00000519225 N/A N/A 0.826±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000521202 0.109±0.00 N/A N/A N/A N/A 0.151±0.00 0.091±0.00 N/A 0.018±0.00 N/A 0.457±0.00 N/A 2.647±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0006TP CIL_0006TP_0001 CGP 1:241652278-241895148

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000737 IDA DNA catabolic process, endonucleolytic
GO:0000738 IDA DNA catabolic process, exonucleolytic
GO:0002455 IEA humoral immune response mediated by circulating immunoglobulin
GO:0003677 IDA:IEA DNA binding
GO:0003824 IEA catalytic activity
GO:0004518 IEA nuclease activity
GO:0004523 TAS RNA-DNA hybrid ribonuclease activity
GO:0004527 TAS exonuclease activity
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0006281 IEA:TAS DNA repair
GO:0006298 IMP mismatch repair
GO:0006310 IGI DNA recombination
GO:0008409 ISS 5'-3' exonuclease activity
GO:0016446 IEA somatic hypermutation of immunoglobulin genes
GO:0035312 IDA 5'-3' exodeoxyribonuclease activity
GO:0043566 IEA structure-specific DNA binding
GO:0045145 IDA single-stranded DNA 5'-3' exodeoxyribonuclease activity
GO:0045190 IEA isotype switching
GO:0046872 IEA metal ion binding
GO:0048256 IDA flap endonuclease activity
GO:0051321 IEA meiotic cell cycle
GO:0051908 IDA double-stranded DNA 5'-3' exodeoxyribonuclease activity
GO:0090305 IEA:TAS nucleic acid phosphodiester bond hydrolysis
GO:0090502 TAS RNA phosphodiester bond hydrolysis, endonucleolytic

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000056832 exo1 exonuclease 1 protein_coding Danio_rerio
ENSMUSG00000039748 Exo1 exonuclease 1 protein_coding Mus_musculus

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