C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: frizzled class receptor 4
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000174804 FZD4 9606 - 11:86945679-86955391 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000531380 FZD4-001 86945679-86955391 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000531380
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000531380 52.456±0.00 12.548±0.00 8.207±0.00 2.208±0.86 41.742±32.77 8.044±2.51 7.690±3.21 8.537±2.56 8.335±3.99 11.995±3.27 4.516±0.82 6.399±3.14 5.630±0.28 4.997±0.89

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008U2 CIL_0008U2_0001 VISTA 11:86595852-87198957

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001553 IEA luteinization
GO:0001568 IEA blood vessel development
GO:0001570 IBA vasculogenesis
GO:0004888 IEA transmembrane signaling receptor activity
GO:0004930 IEA G-protein coupled receptor activity
GO:0005515 IPI:IEA protein binding
GO:0005737 IBA cytoplasm
GO:0005886 IDA plasma membrane
GO:0005887 IC integral component of plasma membrane
GO:0005911 IEA cell-cell junction
GO:0007166 IEA cell surface receptor signaling pathway
GO:0007186 IEA G-protein coupled receptor signaling pathway
GO:0007223 IDA Wnt signaling pathway, calcium modulating pathway
GO:0007420 IBA brain development
GO:0007605 IEA sensory perception of sound
GO:0009986 IDA cell surface
GO:0010812 IMP negative regulation of cell-substrate adhesion
GO:0016020 IEA membrane
GO:0016055 IDA Wnt signaling pathway
GO:0017147 IBA Wnt-protein binding
GO:0019955 IPI cytokine binding
GO:0030165 IPI PDZ domain binding
GO:0030182 ISS neuron differentiation
GO:0030669 TAS clathrin-coated endocytic vesicle membrane
GO:0030947 IBA regulation of vascular endothelial growth factor receptor signaling pathway
GO:0031625 IPI ubiquitin protein ligase binding
GO:0031987 IEA locomotion involved in locomotory behavior
GO:0034446 IBA substrate adhesion-dependent cell spreading
GO:0035426 IEA extracellular matrix-cell signaling
GO:0042701 IBA progesterone secretion
GO:0042803 IPI protein homodimerization activity
GO:0042813 IDA Wnt-activated receptor activity
GO:0042995 IBA cell projection
GO:0043507 IEA positive regulation of JUN kinase activity
GO:0045893 IDA positive regulation of transcription, DNA-templated
GO:0046982 IPI protein heterodimerization activity
GO:0051091 IDA positive regulation of sequence-specific DNA binding transcription factor activity
GO:0060070 IDA canonical Wnt signaling pathway
GO:0061299 IMP retina vasculature morphogenesis in camera-type eye
GO:0061301 IEA cerebellum vasculature morphogenesis
GO:0061304 IEA retinal blood vessel morphogenesis
GO:0070062 IDA extracellular vesicular exosome
GO:0071300 ISS cellular response to retinoic acid

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000077111 fzd4 frizzled homolog 4 protein_coding Danio_rerio
ENSMUSG00000049791 Fzd4 frizzled homolog 4 (Drosophila) protein_coding Mus_musculus

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