C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: solute carrier family 22 (organic cation transporter), member 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000175003 SLC22A1 9606 + 6:160121789-160158718 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000324965 SLC22A1-006 160121936-160158551 protein_coding
  ENST00000366963 SLC22A1-001 160121789-160158718 protein_coding
  ENST00000457470 SLC22A1-007 160121936-160158582 protein_coding
  ENST00000460902 SLC22A1-002 160121936-160158716 nonsense_mediated_decay
  ENST00000478607 SLC22A1-003 160155954-160158718 retained_intron
  ENST00000539263 SLC22A1-004 160121899-160158582 nonsense_mediated_decay
  ENST00000540443 SLC22A1-005 160129761-160134007 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000324965ENST00000366963ENST00000457470ENST00000460902ENST00000478607ENST00000539263ENST00000540443
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000324965 N/A N/A N/A 0.083±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.104±0.00
ENST00000366963 0.054±0.00 N/A N/A N/A N/A N/A N/A 158.320±0.00 69.965±0.00 N/A N/A 0.242±0.00 N/A N/A
ENST00000457470 N/A N/A N/A N/A N/A 0.048±0.00 N/A N/A N/A 0.063±0.00 N/A N/A 0.137±0.00 N/A
ENST00000460902 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.111±0.00 0.077±0.02 N/A N/A
ENST00000478607 N/A N/A N/A N/A N/A 0.433±0.00 0.123±0.00 0.555±0.00 236.432±0.00 N/A 0.121±0.00 0.324±0.00 0.257±0.00 0.364±0.00
ENST00000539263 N/A 0.134±0.00 N/A N/A 0.064±0.00 N/A N/A 0.429±0.00 62.843±62.79 0.057±0.00 N/A 0.084±0.02 0.069±0.03 0.179±0.00
ENST00000540443 N/A 0.290±0.00 0.369±0.00 N/A N/A 0.044±0.00 N/A N/A N/A N/A N/A 0.096±0.01 N/A 0.138±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00089P CIL_00089P_0001 VISTA 6:159654795-160257694
CIL_0002QF CIL_0002QF_0002 CGP 6:159969099-160158718

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005277 IEA acetylcholine transmembrane transporter activity
GO:0005329 IEA dopamine transmembrane transporter activity
GO:0005333 IEA norepinephrine transmembrane transporter activity
GO:0005515 IPI protein binding
GO:0005886 TAS plasma membrane
GO:0005887 TAS integral component of plasma membrane
GO:0006812 IEA cation transport
GO:0006836 IEA neurotransmitter transport
GO:0006855 TAS drug transmembrane transport
GO:0008504 IEA monoamine transmembrane transporter activity
GO:0008513 IEA secondary active organic cation transmembrane transporter activity
GO:0010248 IEA establishment or maintenance of transmembrane electrochemical gradient
GO:0015075 IEA ion transmembrane transporter activity
GO:0015101 TAS organic cation transmembrane transporter activity
GO:0015651 IEA quaternary ammonium group transmembrane transporter activity
GO:0015695 TAS organic cation transport
GO:0015697 IEA quaternary ammonium group transport
GO:0015844 IEA monoamine transport
GO:0015872 IEA dopamine transport
GO:0015874 IEA norepinephrine transport
GO:0016020 TAS membrane
GO:0016021 IEA integral component of membrane
GO:0016323 IEA basolateral plasma membrane
GO:0022857 IEA transmembrane transporter activity
GO:0034220 IEA ion transmembrane transport
GO:0042802 IEA identical protein binding
GO:0042803 IEA protein homodimerization activity
GO:0044281 TAS small molecule metabolic process
GO:0048241 IEA epinephrine transport
GO:0051260 IEA protein homooligomerization
GO:0055085 TAS:IEA transmembrane transport
GO:1901374 IEA acetate ester transport

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000030530 slc22a2 solute carrier family 22 (organic cation transporter), member 2 protein_coding Danio_rerio
ENSMUSG00000023829 Slc22a1 solute carrier family 22 (organic cation transporter), member 1 protein_coding Mus_musculus

Loading