C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: dynactin 2 (p50)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000175203 DCTN2 9606 - 12:57530102-57547331 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000434715 DCTN2-026 57530311-57547141 protein_coding
  ENST00000543672 DCTN2-201 57530689-57547172 protein_coding
  ENST00000546559 DCTN2-009 57542947-57547193 processed_transcript
  ENST00000546670 DCTN2-014 57532994-57547185 protein_coding
  ENST00000546758 DCTN2-023 57530679-57535070 protein_coding
  ENST00000546965 DCTN2-012 57534009-57538552 processed_transcript
  ENST00000547345 DCTN2-013 57534978-57547188 retained_intron
  ENST00000547480 DCTN2-008 57535495-57547206 retained_intron
  ENST00000548249 DCTN2-001 57530102-57547331 protein_coding
  ENST00000548736 DCTN2-020 57532978-57534530 retained_intron
  ENST00000548949 DCTN2-017 57534346-57535845 processed_transcript
  ENST00000549394 DCTN2-006 57530617-57547120 nonsense_mediated_decay
  ENST00000549712 DCTN2-010 57546028-57547174 processed_transcript
  ENST00000550086 DCTN2-018 57532635-57535845 protein_coding
  ENST00000550201 DCTN2-004 57530354-57547152 nonsense_mediated_decay
  ENST00000550576 DCTN2-015 57535484-57536083 retained_intron
  ENST00000550750 DCTN2-007 57534341-57547224 protein_coding
  ENST00000550954 DCTN2-025 57532793-57547121 protein_coding
  ENST00000550988 DCTN2-024 57532267-57533972 retained_intron
  ENST00000551142 DCTN2-019 57534382-57535546 retained_intron
  ENST00000551400 DCTN2-011 57535060-57538566 processed_transcript
  ENST00000551611 DCTN2-016 57533953-57535845 processed_transcript
  ENST00000551872 DCTN2-021 57532795-57534402 retained_intron
  ENST00000552390 DCTN2-022 57532590-57535139 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000434715ENST00000543672ENST00000546559ENST00000546965ENST00000547345ENST00000548249ENST00000550086ENST00000550201ENST00000551400
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000434715 27.821±0.00 30.450±0.00 N/A 52.687±0.00 N/A 47.450±0.00 22.518±0.00 54.208±0.00 17.026±0.00 37.382±0.00 45.211±0.00 23.829±5.61 15.594±5.30 46.268±0.00
ENST00000543672 N/A N/A 2.255±0.00 24.681±15.05 9.729±7.00 N/A 10.081±0.00 N/A 2.454±0.00 N/A 12.848±10.18 20.627±1.14 18.029±0.00 32.738±0.00
ENST00000546559 N/A N/A N/A N/A N/A N/A N/A N/A N/A 11.108±0.00 N/A N/A N/A N/A
ENST00000546965 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 5.119±0.00 N/A N/A
ENST00000547345 N/A N/A N/A N/A 6.795±0.00 12.354±0.00 8.007±0.00 N/A 7.302±0.00 6.254±0.00 N/A 10.786±0.00 N/A N/A
ENST00000548249 N/A 9.550±0.00 N/A N/A 1.363±0.00 5.073±0.00 3.947±1.33 3.732±0.00 2.428±0.00 1.829±0.00 4.564±0.00 15.054±8.33 22.076±7.64 11.615±0.00
ENST00000550086 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 44.563±0.00 30.717±0.00 34.228±0.00
ENST00000550201 N/A N/A N/A N/A 13.473±0.00 N/A 6.885±0.00 N/A N/A 18.422±0.00 N/A 26.229±4.65 20.631±3.22 28.331±0.00
ENST00000551400 N/A N/A 8.078±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000086 TAS G2/M transition of mitotic cell cycle
GO:0000278 TAS mitotic cell cycle
GO:0000776 IDA kinetochore
GO:0003774 IEA motor activity
GO:0005515 IPI protein binding
GO:0005737 IDA cytoplasm
GO:0005813 IDA centrosome
GO:0005829 TAS cytosol
GO:0005869 IDA dynactin complex
GO:0005874 IEA microtubule
GO:0007017 IEA microtubule-based process
GO:0007052 IBA mitotic spindle organization
GO:0007067 IMP mitotic nuclear division
GO:0008152 IEA metabolic process
GO:0008283 IMP cell proliferation
GO:0016020 IEA membrane
GO:0019886 TAS antigen processing and presentation of exogenous peptide antigen via MHC class II
GO:0030286 IEA dynein complex
GO:0030426 IEA growth cone
GO:0030507 IDA spectrin binding
GO:0031982 IDA vesicle
GO:0032402 IEA melanosome transport
GO:0070062 IDA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000031388 dctn2 dynactin 2 (p50) protein_coding Danio_rerio
ENSMUSG00000025410 Dctn2 dynactin 2 protein_coding Mus_musculus

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