C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: Rho GTPase activating protein 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000175220 ARHGAP1 9606 - 11:46677080-46700615 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000311956 ARHGAP1-001 46677080-46700599 protein_coding
  ENST00000524594 ARHGAP1-002 46695083-46700615 retained_intron
  ENST00000525488 ARHGAP1-006 46681069-46697284 protein_coding
  ENST00000526423 ARHGAP1-004 46678723-46681516 retained_intron
  ENST00000527588 ARHGAP1-005 46686747-46697572 retained_intron
  ENST00000528837 ARHGAP1-007 46679217-46696099 protein_coding
  ENST00000529960 ARHGAP1-003 46687691-46700603 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000311956ENST00000525488ENST00000529960
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000311956 87.722±0.00 70.913±0.00 1.981±0.00 22.542±0.00 20.506±17.31 16.623±16.11 13.122±12.29 11.721±10.85 7.976±2.16 11.667±9.39 23.576±0.00 22.528±17.88 41.565±8.42 20.533±17.32
ENST00000525488 N/A N/A N/A N/A N/A N/A 1.594±0.00 N/A N/A N/A N/A 1.413±0.00 N/A N/A
ENST00000529960 N/A N/A N/A N/A N/A N/A N/A 1.088±0.00 N/A N/A N/A N/A N/A N/A

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001726 IEA ruffle
GO:0005070 TAS SH3/SH2 adaptor activity
GO:0005100 IDA Rho GTPase activator activity
GO:0005515 IPI protein binding
GO:0005622 IEA intracellular
GO:0005829 TAS cytosol
GO:0005886 IEA plasma membrane
GO:0007165 IEA signal transduction
GO:0007264 IDA small GTPase mediated signal transduction
GO:0007266 TAS Rho protein signal transduction
GO:0009967 TAS positive regulation of signal transduction
GO:0017124 IEA SH3 domain binding
GO:0030675 IEA Rac GTPase activator activity
GO:0031252 IEA cell leading edge
GO:0032321 IEA positive regulation of Rho GTPase activity
GO:0032855 IEA positive regulation of Rac GTPase activity
GO:0043087 IEA regulation of GTPase activity
GO:0051056 TAS regulation of small GTPase mediated signal transduction
GO:0070062 IDA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000024324 arhgap1 Rho GTPase activating protein 1 protein_coding Danio_rerio
ENSMUSG00000027247 Arhgap1 Rho GTPase activating protein 1 protein_coding Mus_musculus

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