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Institute of Cardiovascular Regeneration Webtool Repository

C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: Rho GTPase activating protein 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000027247 Arhgap1 10090 + 2:91649860-91672326 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000090614 Arhgap1-003 91650222-91672326 protein_coding
  ENSMUST00000111329 Arhgap1-002 91649860-91672326 protein_coding
  ENSMUST00000111330 Arhgap1-201 91653208-91672302 protein_coding
  ENSMUST00000111331 Arhgap1-001 91650118-91672326 protein_coding
  ENSMUST00000123702 Arhgap1-007 91668516-91671361 processed_transcript
  ENSMUST00000139314 Arhgap1-004 91651498-91654531 processed_transcript
  ENSMUST00000141012 Arhgap1-005 91651747-91668328 processed_transcript
  ENSMUST00000149426 Arhgap1-008 91669931-91671047 processed_transcript
  ENSMUST00000154468 Arhgap1-006 91651498-91654533 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000090614ENSMUST00000111329ENSMUST00000111330ENSMUST00000111331ENSMUST00000149426ENSMUST00000154468
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000090614 24.219±5.66 19.540±7.61 23.304±3.20 8.014±2.40 26.559±6.53 66.703±6.44 5.675±3.05 16.285±5.68 7.465±4.70 49.188±3.50 0.954±0.23 36.506±14.44 48.221±25.69 6.918±1.78
ENSMUST00000111329 17.384±5.12 4.911±0.33 12.715±3.13 7.129±0.64 10.375±2.13 N/A 3.622±0.11 6.662±1.42 3.732±1.96 9.125±0.84 0.528±0.16 17.259±3.94 12.072±0.30 2.277±0.58
ENSMUST00000111330 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.335±0.00 N/A N/A N/A
ENSMUST00000111331 11.853±1.20 5.067±0.74 9.366±0.39 8.392±4.50 10.937±2.74 12.782±0.85 4.277±1.79 10.644±3.44 2.648±1.13 13.199±2.33 1.349±0.58 18.146±4.88 10.348±1.25 1.745±0.35
ENSMUST00000149426 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.966±0.00
ENSMUST00000154468 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 51.167±0.00 N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_000182 CIL_000182_0002 CGP 2:91649860-91710576

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001726 IDA ruffle
GO:0005100 IDA Rho GTPase activator activity
GO:0005515 IPI protein binding
GO:0005622 IEA intracellular
GO:0005737 IEA cytoplasm
GO:0005886 IDA plasma membrane
GO:0007165 IEA signal transduction
GO:0007264 IEA small GTPase mediated signal transduction
GO:0017124 IEA SH3 domain binding
GO:0030675 IDA Rac GTPase activator activity
GO:0031252 IDA cell leading edge
GO:0032321 IDA positive regulation of Rho GTPase activity
GO:0032855 IDA positive regulation of Rac GTPase activity
GO:0043087 IDA regulation of GTPase activity
GO:0070062 IEA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000024324 arhgap1 Rho GTPase activating protein 1 protein_coding Danio_rerio
ENSG00000175220 ARHGAP1 Rho GTPase activating protein 1 protein_coding Homo_sapiens

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