C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: cardiotrophin-like cytokine factor 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000175505 CLCF1 9606 - 11:67364168-67374177 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000312438 CLCF1-002 67364168-67373737 protein_coding
  ENST00000533438 CLCF1-001 67364962-67374177 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; HeartKidneyLiverLungOvaryPlacentaENST00000312438ENST00000533438
Transcript ID Heart Kidney Liver Lung Ovary Placenta
ENST00000312438 0.219±0.00 5.438±0.00 0.231±0.00 5.568±0.00 5.845±2.68 6.279±0.00
ENST00000533438 N/A N/A N/A 1.188±0.00 N/A N/A

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0002639 ISS positive regulation of immunoglobulin production
GO:0005102 IPI receptor binding
GO:0005125 NAS cytokine activity
GO:0005127 IDA ciliary neurotrophic factor receptor binding
GO:0005515 IPI protein binding
GO:0005576 NAS extracellular region
GO:0005737 IEA cytoplasm
GO:0007166 ISS cell surface receptor signaling pathway
GO:0007259 ISS JAK-STAT cascade
GO:0008083 TAS growth factor activity
GO:0008284 IDA positive regulation of cell proliferation
GO:0019221 NAS cytokine-mediated signaling pathway
GO:0030183 ISS B cell differentiation
GO:0030890 ISS positive regulation of B cell proliferation
GO:0040007 IEA growth
GO:0042517 IDA positive regulation of tyrosine phosphorylation of Stat3 protein
GO:0043524 IDA negative regulation of neuron apoptotic process
GO:0046982 IDA protein heterodimerization activity
GO:0048295 ISS positive regulation of isotype switching to IgE isotypes
GO:0048711 ISS positive regulation of astrocyte differentiation
GO:0070062 IDA extracellular vesicular exosome
GO:0097058 IDA CRLF-CLCF1 complex
GO:0097059 IDA CNTFR-CLCF1 complex

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000076140 clcf1 cardiotrophin-like cytokine factor 1 protein_coding Danio_rerio
ENSMUSG00000040663 Clcf1 cardiotrophin-like cytokine factor 1 protein_coding Mus_musculus

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