C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: ribosomal protein S6 kinase, 70kDa, polypeptide 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000175634 RPS6KB2 9606 + 11:67428460-67435408 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000312629 RPS6KB2-003 67428501-67435408 protein_coding
  ENST00000420069 RPS6KB2-009 67428498-67432995 protein_coding
  ENST00000524814 RPS6KB2-013 67428494-67432981 processed_transcript
  ENST00000524934 RPS6KB2-006 67428494-67431403 protein_coding
  ENST00000525088 RPS6KB2-004 67428505-67435401 retained_intron
  ENST00000525726 RPS6KB2-011 67432240-67432815 retained_intron
  ENST00000525996 RPS6KB2-010 67429527-67435018 nonsense_mediated_decay
  ENST00000526268 RPS6KB2-007 67432776-67434644 retained_intron
  ENST00000528964 RPS6KB2-005 67428504-67435344 nonsense_mediated_decay
  ENST00000530623 RPS6KB2-008 67428460-67431582 retained_intron
  ENST00000531765 RPS6KB2-012 67433444-67434954 retained_intron
  ENST00000556575 RPS6KB2-014 67428483-67432985 nonsense_mediated_decay

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000312629ENST00000524814ENST00000524934ENST00000525088ENST00000525996ENST00000526268ENST00000528964ENST00000530623ENST00000556575
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000312629 1.763±0.00 N/A 1.628±0.00 0.648±0.00 1.492±0.75 1.596±0.27 1.024±0.66 5.423±0.00 2.075±0.00 1.400±0.00 3.634±0.71 6.953±3.76 12.580±5.57 1.708±0.00
ENST00000524814 5.879±0.00 N/A N/A 5.868±0.00 8.142±0.00 N/A 6.547±0.00 9.901±0.00 N/A N/A N/A 24.170±0.00 43.118±0.00 5.498±0.00
ENST00000524934 N/A N/A 1.531±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000525088 0.624±0.00 2.494±0.00 0.231±0.00 0.688±0.00 N/A 0.346±0.07 N/A 0.686±0.00 N/A 0.807±0.00 0.290±0.00 1.098±0.16 N/A 0.614±0.15
ENST00000525996 4.025±0.00 10.850±0.00 N/A 3.177±0.00 6.873±0.00 4.374±0.00 4.020±0.00 7.008±0.00 10.079±0.00 6.085±0.00 3.896±0.00 7.724±0.00 N/A 4.407±0.00
ENST00000526268 6.328±0.00 18.098±0.00 N/A 3.680±0.00 3.608±1.41 5.098±0.00 4.019±0.00 9.394±0.00 N/A 4.422±2.44 6.535±0.00 7.544±0.00 N/A 6.089±0.00
ENST00000528964 N/A N/A N/A 0.431±0.00 N/A N/A 0.853±0.00 N/A N/A 4.115±0.00 N/A 4.859±0.00 N/A 1.850±0.05
ENST00000530623 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 3.264±0.00 N/A N/A N/A
ENST00000556575 N/A N/A N/A 1.113±0.00 1.042±0.00 N/A N/A N/A N/A N/A N/A N/A N/A 4.462±0.00

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004672 TAS:IEA protein kinase activity
GO:0004674 TAS:IEA protein serine/threonine kinase activity
GO:0004711 IEA ribosomal protein S6 kinase activity
GO:0004713 IEA protein tyrosine kinase activity
GO:0005524 IEA ATP binding
GO:0005654 TAS nucleoplasm
GO:0005737 IEA cytoplasm
GO:0006412 TAS translation
GO:0006468 IEA protein phosphorylation
GO:0007165 TAS:IEA signal transduction
GO:0007173 TAS epidermal growth factor receptor signaling pathway
GO:0008543 TAS fibroblast growth factor receptor signaling pathway
GO:0016772 IEA transferase activity, transferring phosphorus-containing groups
GO:0038095 TAS Fc-epsilon receptor signaling pathway
GO:0042277 IEA peptide binding
GO:0043491 IEA protein kinase B signaling
GO:0045087 TAS innate immune response
GO:0045948 IMP positive regulation of translational initiation
GO:0048011 TAS neurotrophin TRK receptor signaling pathway
GO:0048015 TAS phosphatidylinositol-mediated signaling

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSMUSG00000024830 Rps6kb2 ribosomal protein S6 kinase, polypeptide 2 protein_coding Mus_musculus

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