C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: ribosomal protein S6 kinase, polypeptide 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000024830 Rps6kb2 10090 - 19:4156713-4163354 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000025749 Rps6kb2-001 4156713-4163354 protein_coding
  ENSMUST00000118483 Rps6kb2-006 4156986-4163285 protein_coding
  ENSMUST00000125057 Rps6kb2-012 4162815-4163354 processed_transcript
  ENSMUST00000127605 Rps6kb2-004 4156792-4163296 nonsense_mediated_decay
  ENSMUST00000130469 Rps6kb2-003 4156795-4163300 nonsense_mediated_decay
  ENSMUST00000135911 Rps6kb2-008 4156986-4162330 processed_transcript
  ENSMUST00000137431 Rps6kb2-005 4156986-4163285 nonsense_mediated_decay
  ENSMUST00000141104 Rps6kb2-011 4156795-4158152 retained_intron
  ENSMUST00000151727 Rps6kb2-009 4162517-4163330 retained_intron
  ENSMUST00000154307 Rps6kb2-002 4156795-4163316 retained_intron
  ENSMUST00000155303 Rps6kb2-010 4162260-4163300 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000025749ENSMUST00000127605ENSMUST00000130469ENSMUST00000137431ENSMUST00000141104ENSMUST00000151727ENSMUST00000154307
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000025749 5.805±1.00 6.140±0.00 6.147±0.39 6.091±1.10 N/A 3.704±0.41 3.304±1.45 6.499±0.56 5.766±1.30 9.301±0.00 7.072±0.76 3.898±0.89 9.340±2.99 0.949±0.53
ENSMUST00000127605 N/A 9.087±2.31 N/A 3.681±0.00 N/A 4.084±0.00 1.486±0.00 2.823±0.17 2.743±0.19 N/A 2.725±0.86 5.256±2.03 N/A N/A
ENSMUST00000130469 3.131±0.01 3.596±0.00 4.894±0.51 11.252±5.96 N/A N/A 2.264±0.28 2.130±0.00 N/A 3.647±0.26 2.054±0.04 1.893±0.52 2.875±1.40 0.875±0.37
ENSMUST00000137431 6.336±0.00 7.872±1.92 N/A N/A 15.159±1.35 5.942±0.46 2.307±0.48 4.676±0.89 3.703±0.92 N/A N/A 6.875±1.72 N/A 1.014±0.21
ENSMUST00000141104 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 16.470±0.00 N/A
ENSMUST00000151727 N/A N/A N/A 24.927±0.00 N/A N/A N/A N/A N/A N/A N/A 22.393±0.00 44.718±9.29 3.253±0.00
ENSMUST00000154307 3.327±0.00 7.300±1.98 4.946±0.00 3.813±1.17 5.895±2.10 3.927±1.15 1.576±0.25 3.608±0.59 3.571±1.12 5.084±0.00 1.666±0.12 5.025±2.59 3.796±1.57 0.928±0.17

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004672 IDA protein kinase activity
GO:0004674 IEA protein serine/threonine kinase activity
GO:0004711 IEA ribosomal protein S6 kinase activity
GO:0005524 IEA ATP binding
GO:0005634 IEA nucleus
GO:0005737 IEA cytoplasm
GO:0006468 IDA protein phosphorylation
GO:0042277 IEA peptide binding
GO:0043491 IGI protein kinase B signaling
GO:0045948 IEA positive regulation of translational initiation

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSG00000175634 RPS6KB2 ribosomal protein S6 kinase, 70kDa, polypeptide 2 protein_coding Homo_sapiens

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