C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: YES proto-oncogene 1, Src family tyrosine kinase
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000176105 YES1 9606 - 18:721588-812546 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000314574 YES1-003 721748-812238 protein_coding
  ENST00000577611 YES1-005 751724-812266 processed_transcript
  ENST00000577961 YES1-006 721588-775266 protein_coding
  ENST00000581960 YES1-004 756677-812357 processed_transcript
  ENST00000584307 YES1-002 721588-812546 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000314574ENST00000577961ENST00000584307
Transcript ID Adipose Adrenal Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000314574 20.427±0.00 7.872±0.00 5.393±0.00 7.178±1.98 10.731±2.96 3.247±2.03 6.438±2.50 6.890±1.04 10.244±8.08 1.759±1.54 3.761±2.57 8.966±1.88 10.079±1.48
ENST00000577961 N/A N/A 2.099±0.00 N/A 3.016±0.00 N/A 7.148±0.00 N/A 4.121±0.00 N/A N/A N/A N/A
ENST00000584307 4.303±0.00 N/A 0.849±0.00 1.928±0.00 1.728±0.00 1.117±0.00 1.924±0.00 1.968±0.00 1.878±0.00 N/A 4.827±1.35 1.960±0.42 N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00025N CIL_00025N_0002 CGP 18:721588-912172

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004672 IEA protein kinase activity
GO:0004713 TAS:IEA protein tyrosine kinase activity
GO:0004715 TAS non-membrane spanning protein tyrosine kinase activity
GO:0005154 IEA epidermal growth factor receptor binding
GO:0005515 IPI:IEA protein binding
GO:0005524 IEA ATP binding
GO:0005737 IDA cytoplasm
GO:0005794 IDA Golgi apparatus
GO:0005829 TAS cytosol
GO:0005856 IEA cytoskeleton
GO:0005884 IEA actin filament
GO:0005886 IDA plasma membrane
GO:0005925 IDA focal adhesion
GO:0006464 TAS cellular protein modification process
GO:0006468 IEA protein phosphorylation
GO:0007596 TAS blood coagulation
GO:0015758 IEA glucose transport
GO:0016772 IEA transferase activity, transferring phosphorus-containing groups
GO:0018108 IEA peptidyl-tyrosine phosphorylation
GO:0019899 IPI enzyme binding
GO:0031295 TAS T cell costimulation
GO:0036120 IEA cellular response to platelet-derived growth factor stimulus
GO:0038096 TAS Fc-gamma receptor signaling pathway involved in phagocytosis
GO:0043114 TAS regulation of vascular permeability
GO:0044325 IPI ion channel binding
GO:0045087 TAS innate immune response
GO:0046777 IEA protein autophosphorylation
GO:0050900 TAS leukocyte migration
GO:0070062 IDA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000005941 yes1 v-yes-1 Yamaguchi sarcoma viral oncogene homolog 1 protein_coding Danio_rerio
ENSMUSG00000014932 Yes1 Yamaguchi sarcoma viral (v-yes) oncogene homolog 1 protein_coding Mus_musculus

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