C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: YES proto-oncogene 1, Src family tyrosine kinase
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000584307 YES1-002 ENSG00000176105 9606 - 18:721588-812546 protein_coding

Homo sapiens EnsemblGRCh38

Genome
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Genes
Structures from Ensembl
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Transcripts
Structures from Ensembl
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Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeBrainBreastColonHeartKidneyLiverLungOvaryPlacentaENST00000584307
Transcript ID Adipose Brain Breast Colon Heart Kidney Liver Lung Ovary Placenta
ENST00000584307 4.303±0.00 0.849±0.00 1.928±0.00 1.728±0.00 1.117±0.00 1.924±0.00 1.968±0.00 1.878±0.00 4.827±1.35 1.960±0.42

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00025N CIL_00025N_0002 CGP 18:721588-912172

Gene Ontology

GO IDEvidence TypeGO Description
GO:0004672 IEA protein kinase activity
GO:0004713 TAS:IEA protein tyrosine kinase activity
GO:0004715 TAS non-membrane spanning protein tyrosine kinase activity
GO:0005154 IEA epidermal growth factor receptor binding
GO:0005515 IPI:IEA protein binding
GO:0005524 IEA ATP binding
GO:0005737 IDA cytoplasm
GO:0005794 IDA Golgi apparatus
GO:0005829 TAS cytosol
GO:0005856 IEA cytoskeleton
GO:0005884 IEA actin filament
GO:0005886 IDA plasma membrane
GO:0005925 IDA focal adhesion
GO:0006464 TAS cellular protein modification process
GO:0006468 IEA protein phosphorylation
GO:0007596 TAS blood coagulation
GO:0015758 IEA glucose transport
GO:0016772 IEA transferase activity, transferring phosphorus-containing groups
GO:0018108 IEA peptidyl-tyrosine phosphorylation
GO:0019899 IPI enzyme binding
GO:0031295 TAS T cell costimulation
GO:0036120 IEA cellular response to platelet-derived growth factor stimulus
GO:0038096 TAS Fc-gamma receptor signaling pathway involved in phagocytosis
GO:0043114 TAS regulation of vascular permeability
GO:0044325 IPI ion channel binding
GO:0045087 TAS innate immune response
GO:0046777 IEA protein autophosphorylation
GO:0050900 TAS leukocyte migration
GO:0070062 IDA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000072311 Yes1-201 protein_coding Mus_musculus 0 2405
ENSMUST00000168707 Yes1-202 protein_coding Mus_musculus 0 2255
ENSMUST00000146287 Fyn-005 protein_coding Mus_musculus 0 459
ENSMUST00000135242 Fyn-004 protein_coding Mus_musculus 0 459
ENSMUST00000126486 Fyn-003 protein_coding Mus_musculus 0 459
ENSMUST00000063091 Fyn-001 protein_coding Mus_musculus 0 459
ENSMUST00000120027 Gm15967-001 processed_pseudogene Mus_musculus 0 409
ENSMUST00000099967 Fyn-002 protein_coding Mus_musculus 0 405
ENSMUST00000136659 Fyn-008 protein_coding Mus_musculus 0 276
ENSMUST00000123205 Fyn-009 processed_transcript Mus_musculus 6e-26 124

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