C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: cell death-inducing DFFA-like effector a
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000176194 CIDEA 9606 + 18:12254319-12277595 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000320477 CIDEA-002 12254319-12277373 protein_coding
  ENST00000520620 CIDEA-004 12254725-12277481 processed_transcript
  ENST00000521296 CIDEA-001 12254702-12277595 processed_transcript
  ENST00000522713 CIDEA-003 12254361-12277593 nonsense_mediated_decay

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000320477ENST00000520620ENST00000521296ENST00000522713
Transcript ID Adipose Adrenal Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000320477 169.271±0.00 0.221±0.00 0.582±0.05 32.488±31.49 1.193±0.00 0.485±0.14 0.085±0.00 3.734±0.00 0.428±0.16 N/A 0.276±0.15 0.166±0.00 0.241±0.00
ENST00000520620 N/A N/A N/A N/A N/A 0.470±0.35 N/A N/A N/A N/A N/A 0.084±0.00 N/A
ENST00000521296 114.968±0.00 N/A 0.698±0.54 22.387±21.77 5.097±0.00 0.146±0.00 N/A 0.447±0.00 N/A 0.327±0.00 N/A N/A 0.596±0.00
ENST00000522713 N/A N/A N/A N/A 0.399±0.00 N/A N/A N/A N/A N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007ZP CIL_0007ZP_0001 VISTA 18:11977697-12581651
CIL_00025T CIL_00025T_0002 CGP 18:12254319-12344320

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001659 ISS temperature homeostasis
GO:0005515 IEA protein binding
GO:0005622 IEA intracellular
GO:0005634 ISS nucleus
GO:0005737 ISS cytoplasm
GO:0005739 ISS mitochondrion
GO:0005740 ISS mitochondrial envelope
GO:0005811 IDA lipid particle
GO:0006351 IEA transcription, DNA-templated
GO:0006355 IEA regulation of transcription, DNA-templated
GO:0006629 ISS lipid metabolic process
GO:0006915 IEA apoptotic process
GO:0008219 ISS cell death
GO:0010890 ISS positive regulation of sequestering of triglyceride
GO:0019915 ISS lipid storage
GO:0030512 ISS negative regulation of transforming growth factor beta receptor signaling pathway
GO:0032720 IMP negative regulation of tumor necrosis factor production
GO:0035634 IEA response to stilbenoid
GO:0042803 ISS protein homodimerization activity
GO:0042981 IBA regulation of apoptotic process
GO:0050710 IMP negative regulation of cytokine secretion
GO:0050995 ISS negative regulation of lipid catabolic process
GO:1900118 ISS negative regulation of execution phase of apoptosis
GO:1902510 ISS regulation of apoptotic DNA fragmentation

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000061267 cidea cell death-inducing DFFA-like effector a protein_coding Danio_rerio
ENSMUSG00000024526 Cidea cell death-inducing DNA fragmentation factor, alpha subunit-like effector A protein_coding Mus_musculus

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