C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: CDC-like kinase 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000176444 CLK2 9606 - 1:155262868-155278491 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000355560 CLK2-003 155262874-155273482 protein_coding
  ENST00000361168 CLK2-002 155262868-155273287 protein_coding
  ENST00000368361 CLK2-001 155262868-155273516 protein_coding
  ENST00000471047 CLK2-006 155268094-155278491 processed_transcript
  ENST00000476983 CLK2-004 155262874-155273329 processed_transcript
  ENST00000484699 CLK2-007 155269166-155270841 processed_transcript
  ENST00000497188 CLK2-005 155262880-155269363 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000355560ENST00000361168ENST00000368361ENST00000471047ENST00000476983ENST00000484699ENST00000497188
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000355560 2.388±0.00 N/A N/A N/A 1.068±0.02 3.932±0.00 N/A 3.325±0.00 0.774±0.16 6.106±0.00 1.182±0.00 3.775±0.59 2.511±0.00 4.376±0.00
ENST00000361168 1.712±0.00 N/A N/A N/A 2.946±1.04 1.722±0.00 1.000±0.00 N/A N/A 1.490±0.00 3.547±0.00 5.005±3.39 5.094±0.69 N/A
ENST00000368361 3.496±0.00 5.920±0.00 N/A 2.186±0.00 2.460±0.00 2.802±1.94 1.220±0.00 6.678±0.00 N/A 2.113±0.00 3.103±0.00 4.964±1.33 5.971±1.09 5.393±0.00
ENST00000471047 N/A N/A N/A N/A N/A N/A N/A 4.534±0.00 N/A N/A N/A N/A N/A N/A
ENST00000476983 N/A 10.253±0.00 N/A 1.389±0.99 N/A N/A 1.646±0.00 3.611±0.00 3.372±0.94 N/A N/A 7.461±4.47 4.494±0.00 7.418±0.00
ENST00000484699 N/A N/A 7.326±0.00 N/A N/A N/A N/A 4.778±0.00 N/A N/A N/A N/A N/A N/A
ENST00000497188 N/A 5.447±0.00 N/A 0.903±0.00 0.996±0.00 1.646±0.00 0.514±0.16 1.902±0.75 0.581±0.02 0.993±0.00 N/A 3.826±1.20 N/A N/A

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004672 IEA protein kinase activity
GO:0004674 IEA protein serine/threonine kinase activity
GO:0004712 IEA protein serine/threonine/tyrosine kinase activity
GO:0004713 IEA protein tyrosine kinase activity
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0005634 IDA nucleus
GO:0006468 IEA protein phosphorylation
GO:0010033 IEA response to organic substance
GO:0010212 IMP response to ionizing radiation
GO:0016772 IEA transferase activity, transferring phosphorus-containing groups
GO:0018108 IEA peptidyl-tyrosine phosphorylation
GO:0032526 IEA response to retinoic acid
GO:0043484 IDA regulation of RNA splicing
GO:0045721 ISS negative regulation of gluconeogenesis
GO:0046777 ISS protein autophosphorylation

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000059870 clk2b CDC-like kinase 2b protein_coding Danio_rerio
ENSDARG00000062954 clk2a CDC-like kinase 2a protein_coding Danio_rerio
ENSMUSG00000068917 Clk2 CDC-like kinase 2 protein_coding Mus_musculus

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