C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: ribosomal protein S6 kinase, 90kDa, polypeptide 3
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000177189 RPS6KA3 9606 - X:20149911-20267100 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000379565 RPS6KA3-001 20149911-20266840 protein_coding
  ENST00000438357 RPS6KA3-003 20194192-20266642 protein_coding
  ENST00000457145 RPS6KA3-002 20187832-20218959 protein_coding
  ENST00000474266 RPS6KA3-004 20203362-20218870 retained_intron
  ENST00000479809 RPS6KA3-005 20155441-20172864 processed_transcript
  ENST00000492128 RPS6KA3-006 20193520-20267100 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000379565ENST00000479809
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000379565 6.908±0.00 6.497±0.00 0.646±0.00 3.628±0.32 7.399±2.80 13.491±0.00 3.836±0.80 1.476±0.02 3.997±2.78 5.451±1.29 4.192±2.84 5.009±2.77 3.328±0.24 2.862±1.82
ENST00000479809 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 14.917±0.00 10.367±0.00 4.069±0.00 2.641±0.00

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000287 IEA magnesium ion binding
GO:0001501 TAS skeletal system development
GO:0002224 ISS toll-like receptor signaling pathway
GO:0002755 TAS MyD88-dependent toll-like receptor signaling pathway
GO:0002756 TAS MyD88-independent toll-like receptor signaling pathway
GO:0004672 TAS:IEA protein kinase activity
GO:0004674 IEA protein serine/threonine kinase activity
GO:0004713 IEA protein tyrosine kinase activity
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0005654 TAS nucleoplasm
GO:0005829 TAS cytosol
GO:0006468 IEA protein phosphorylation
GO:0007049 IEA cell cycle
GO:0007165 TAS signal transduction
GO:0007268 TAS synaptic transmission
GO:0007411 TAS axon guidance
GO:0007417 TAS central nervous system development
GO:0009103 IEA lipopolysaccharide biosynthetic process
GO:0016020 IEA membrane
GO:0016772 IEA transferase activity, transferring phosphorus-containing groups
GO:0016773 IEA phosphotransferase activity, alcohol group as acceptor
GO:0019901 IEA protein kinase binding
GO:0030307 TAS positive regulation of cell growth
GO:0032496 ISS response to lipopolysaccharide
GO:0034134 TAS toll-like receptor 2 signaling pathway
GO:0034138 TAS toll-like receptor 3 signaling pathway
GO:0034142 TAS toll-like receptor 4 signaling pathway
GO:0034146 TAS toll-like receptor 5 signaling pathway
GO:0034162 TAS toll-like receptor 9 signaling pathway
GO:0034166 TAS toll-like receptor 10 signaling pathway
GO:0035556 IEA intracellular signal transduction
GO:0035666 TAS TRIF-dependent toll-like receptor signaling pathway
GO:0038123 TAS toll-like receptor TLR1:TLR2 signaling pathway
GO:0038124 TAS toll-like receptor TLR6:TLR2 signaling pathway
GO:0043027 IDA cysteine-type endopeptidase inhibitor activity involved in apoptotic process
GO:0043066 TAS negative regulation of apoptotic process
GO:0043154 IDA negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0043555 TAS regulation of translation in response to stress
GO:0043620 TAS regulation of DNA-templated transcription in response to stress
GO:0045087 TAS innate immune response
GO:0045597 TAS positive regulation of cell differentiation
GO:0045944 IMP positive regulation of transcription from RNA polymerase II promoter
GO:0048011 TAS neurotrophin TRK receptor signaling pathway
GO:0051403 TAS stress-activated MAPK cascade

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000035556 rps6ka3a ribosomal protein S6 kinase, polypeptide 3a protein_coding Danio_rerio
ENSDARG00000057927 rps6ka3b ribosomal protein S6 kinase, polypeptide 3b protein_coding Danio_rerio
ENSMUSG00000031309 Rps6ka3 ribosomal protein S6 kinase polypeptide 3 protein_coding Mus_musculus

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