C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: ribosomal protein S6 kinase, 90kDa, polypeptide 3
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000379565 RPS6KA3-001 ENSG00000177189 9606 - X:20149911-20266840 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000379565
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000379565 6.908±0.00 6.497±0.00 0.646±0.00 3.628±0.32 7.399±2.80 13.491±0.00 3.836±0.80 1.476±0.02 3.997±2.78 5.451±1.29 4.192±2.84 5.009±2.77 3.328±0.24 2.862±1.82

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000287 IEA magnesium ion binding
GO:0001501 TAS skeletal system development
GO:0002224 ISS toll-like receptor signaling pathway
GO:0002755 TAS MyD88-dependent toll-like receptor signaling pathway
GO:0002756 TAS MyD88-independent toll-like receptor signaling pathway
GO:0004672 TAS:IEA protein kinase activity
GO:0004674 IEA protein serine/threonine kinase activity
GO:0004713 IEA protein tyrosine kinase activity
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0005654 TAS nucleoplasm
GO:0005829 TAS cytosol
GO:0006468 IEA protein phosphorylation
GO:0007049 IEA cell cycle
GO:0007165 TAS signal transduction
GO:0007268 TAS synaptic transmission
GO:0007411 TAS axon guidance
GO:0007417 TAS central nervous system development
GO:0009103 IEA lipopolysaccharide biosynthetic process
GO:0016020 IEA membrane
GO:0016772 IEA transferase activity, transferring phosphorus-containing groups
GO:0016773 IEA phosphotransferase activity, alcohol group as acceptor
GO:0019901 IEA protein kinase binding
GO:0030307 TAS positive regulation of cell growth
GO:0032496 ISS response to lipopolysaccharide
GO:0034134 TAS toll-like receptor 2 signaling pathway
GO:0034138 TAS toll-like receptor 3 signaling pathway
GO:0034142 TAS toll-like receptor 4 signaling pathway
GO:0034146 TAS toll-like receptor 5 signaling pathway
GO:0034162 TAS toll-like receptor 9 signaling pathway
GO:0034166 TAS toll-like receptor 10 signaling pathway
GO:0035556 IEA intracellular signal transduction
GO:0035666 TAS TRIF-dependent toll-like receptor signaling pathway
GO:0038123 TAS toll-like receptor TLR1:TLR2 signaling pathway
GO:0038124 TAS toll-like receptor TLR6:TLR2 signaling pathway
GO:0043027 IDA cysteine-type endopeptidase inhibitor activity involved in apoptotic process
GO:0043066 TAS negative regulation of apoptotic process
GO:0043154 IDA negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0043555 TAS regulation of translation in response to stress
GO:0043620 TAS regulation of DNA-templated transcription in response to stress
GO:0045087 TAS innate immune response
GO:0045597 TAS positive regulation of cell differentiation
GO:0045944 IMP positive regulation of transcription from RNA polymerase II promoter
GO:0048011 TAS neurotrophin TRK receptor signaling pathway
GO:0051403 TAS stress-activated MAPK cascade

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000033671 Rps6ka3-001 protein_coding Mus_musculus 0 4608
ENSMUST00000112493 Rps6ka3-002 protein_coding Mus_musculus 0 4252
ENSMUST00000112491 Rps6ka3-004 protein_coding Mus_musculus 0 929
ENSMUST00000148570 Rps6ka3-008 protein_coding Mus_musculus 0 734
ENSMUST00000149939 Rps6ka3-005 retained_intron Mus_musculus 0 693
ENSMUST00000112492 Rps6ka3-007 protein_coding Mus_musculus 0 691
ENSMUST00000156648 Rps6ka3-009 protein_coding Mus_musculus 0 496
ENSMUST00000142668 Rps6ka3-006 processed_transcript Mus_musculus 0 427
ENSMUST00000126686 Rps6ka3-003 protein_coding Mus_musculus 0 211

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