Institute of Cardiovascular Regeneration Webtool Repository

C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info
Description:	p53-induced death domain protein 1
Gene Accession	Gene Name	Tax ID	Strand	Position	Gene Biotype
ENSG00000177595	PIDD1	9606	-	11:799179-809753	protein_coding
	Transcript Accession		Transcript Name	Position	Transcript Biotype
	ENST00000347755		PIDD1-001	799184-805245	protein_coding
	ENST00000411829		PIDD1-002	799184-804469	protein_coding
	ENST00000524486		PIDD1-011	799180-805103	nonsense_mediated_decay
	ENST00000525028		PIDD1-003	799179-804675	nonsense_mediated_decay
	ENST00000527357		PIDD1-010	799185-805230	retained_intron
	ENST00000527812		PIDD1-013	799326-802086	processed_transcript
	ENST00000528122		PIDD1-012	802323-803149	processed_transcript
	ENST00000530911		PIDD1-007	805777-809753	processed_transcript
	ENST00000531286		PIDD1-005	799185-802750	nonsense_mediated_decay
	ENST00000534525		PIDD1-006	799185-809499	retained_intron
	ENST00000534649		PIDD1-008	803376-809523	processed_transcript

Expression Patterns

No expression data.

Conserved Regions
Region ID	Sub-Region	Region Type	Position
CIL_0003EP	CIL_0003EP_0001	CGP	11:799179-812880

Gene Ontology
GO ID	Evidence Type	GO Description
GO:0005123	TAS	death receptor binding
GO:0005515	IPI:IEA	protein binding
GO:0005634	IMP	nucleus
GO:0005737	IDA	cytoplasm
GO:0005794	IDA	Golgi apparatus
GO:0006915	IEA	apoptotic process
GO:0006919	IEA	activation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0006974	IDA:IEA	cellular response to DNA damage stimulus
GO:0006977	IMP	DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
GO:0007165	TAS:IEA	signal transduction
GO:0043065	TAS	positive regulation of apoptotic process
GO:0043066	IMP	negative regulation of apoptotic process
GO:0051092	TAS	positive regulation of NF-kappaB transcription factor activity
GO:1902043	IEA	positive regulation of extrinsic apoptotic signaling pathway via death domain receptors
GO:2001235	IEA	positive regulation of apoptotic signaling pathway
GO:2001238	IEA	positive regulation of extrinsic apoptotic signaling pathway

Homologs
ENSEMBL Accession	Gene Name	Description	Biotype	Species
ENSDARG00000074626	pidd	p53-induced death domain protein	protein_coding	Danio_rerio
ENSMUSG00000025507	Pidd1	p53 induced death domain protein 1	protein_coding	Mus_musculus

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