C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: 5-oxoprolinase (ATP-hydrolysing)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000178814 OPLAH 9606 - 8:144051266-144063832 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000527993 OPLAH-005 144052770-144054653 retained_intron
  ENST00000531027 OPLAH-004 144053213-144054879 retained_intron
  ENST00000567871 OPLAH-006 144058887-144063832 protein_coding
  ENST00000618853 OPLAH-001 144051266-144060703 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000531027ENST00000567871ENST00000618853
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000531027 N/A N/A N/A N/A N/A 0.950±0.00 N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000567871 N/A N/A 0.953±0.00 N/A 0.985±0.00 N/A 1.142±0.00 2.156±0.00 N/A N/A N/A N/A N/A N/A
ENST00000618853 2.570±0.00 1.680±0.00 0.306±0.00 0.755±0.66 3.923±3.57 1.229±0.87 5.056±4.57 5.555±3.41 4.340±3.91 1.525±0.00 8.459±4.86 3.902±2.11 1.566±0.42 18.927±1.57

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007SS CIL_0007SS_0001 VISTA 8:143880613-144482307
CIL_00026X CIL_00026X_0001 CGP 8:144051266-144080647

Gene Ontology

GO IDEvidence TypeGO Description
GO:0003824 IEA catalytic activity
GO:0005524 IEA ATP binding
GO:0005829 TAS cytosol
GO:0006750 TAS glutathione biosynthetic process
GO:0006805 TAS xenobiotic metabolic process
GO:0016787 IEA hydrolase activity
GO:0017168 TAS 5-oxoprolinase (ATP-hydrolyzing) activity
GO:0044281 TAS small molecule metabolic process
GO:1901687 TAS glutathione derivative biosynthetic process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000045123 OPLAH 5-oxoprolinase (ATP-hydrolysing) protein_coding Danio_rerio
ENSMUSG00000022562 Oplah 5-oxoprolinase (ATP-hydrolysing) protein_coding Mus_musculus

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