C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: exosome component 4
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000178896 EXOSC4 9606 + 8:144078626-144080647 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000316052 EXOSC4-001 144078626-144080647 protein_coding
  ENST00000525936 EXOSC4-002 144078648-144080516 protein_coding
  ENST00000527954 EXOSC4-003 144079423-144080579 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000316052ENST00000525936ENST00000527954
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000316052 12.453±0.00 19.703±0.00 1.418±0.00 6.865±4.11 10.366±8.29 6.425±5.49 3.686±3.15 12.038±8.96 8.444±7.14 4.163±3.73 4.143±1.75 14.681±6.07 18.898±10.54 27.254±12.13
ENST00000525936 N/A N/A N/A 3.627±0.00 N/A 3.057±2.01 2.204±0.00 5.327±2.61 2.757±2.34 1.791±1.31 4.151±0.00 2.950±0.73 3.313±0.00 17.345±2.20
ENST00000527954 N/A N/A 0.775±0.00 N/A 0.224±0.00 N/A N/A N/A N/A N/A N/A 0.682±0.00 N/A 1.818±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007SS CIL_0007SS_0001 VISTA 8:143880613-144482307
CIL_00026X CIL_00026X_0001 CGP 8:144051266-144080647
CIL_00026Y CIL_00026Y_0001 CGP 8:144078626-144086216

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000175 NAS 3'-5'-exoribonuclease activity
GO:0000178 IDA exosome (RNase complex)
GO:0000288 TAS nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay
GO:0000460 IMP maturation of 5.8S rRNA
GO:0000956 IMP nuclear-transcribed mRNA catabolic process
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005730 NAS nucleolus
GO:0005737 NAS cytoplasm
GO:0005829 TAS cytosol
GO:0006364 NAS rRNA processing
GO:0010467 TAS gene expression
GO:0016070 TAS RNA metabolic process
GO:0016071 TAS mRNA metabolic process
GO:0017091 IDA AU-rich element binding
GO:0030307 IMP positive regulation of cell growth
GO:0035327 IMP transcriptionally active chromatin
GO:0043928 TAS exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay
GO:0045006 IDA DNA deamination
GO:0051607 IMP defense response to virus
GO:0071028 IMP nuclear mRNA surveillance
GO:0071044 IMP histone mRNA catabolic process
GO:0090503 NAS RNA phosphodiester bond hydrolysis, exonucleolytic

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000088210 exosc4 exosome component 4 protein_coding Danio_rerio
ENSMUSG00000034259 Exosc4 exosome component 4 protein_coding Mus_musculus

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