C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: cytochrome P450, family 8, subfamily B, polypeptide 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000180432 CYP8B1 9606 - 3:42856005-42876165 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000316161 CYP8B1-001 42872192-42876165 protein_coding
  ENST00000437102 CYP8B1-002 42856005-42875898 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BladderHeartKidneyLiverPlacentaENST00000316161
Transcript ID Bladder Heart Kidney Liver Placenta
ENST00000316161 1.068±0.00 0.336±0.00 23.024±15.93 111.208±0.00 5.774±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0003EY CIL_0003EY_0001 CGP 3:42757177-42887974

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004497 IEA monooxygenase activity
GO:0005506 IEA iron ion binding
GO:0005783 IBA endoplasmic reticulum
GO:0005789 TAS endoplasmic reticulum membrane
GO:0006629 IBA lipid metabolic process
GO:0006699 TAS bile acid biosynthetic process
GO:0006805 TAS xenobiotic metabolic process
GO:0008206 TAS bile acid metabolic process
GO:0008397 IBA sterol 12-alpha-hydroxylase activity
GO:0016021 IEA integral component of membrane
GO:0016125 TAS sterol metabolic process
GO:0016705 IEA oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
GO:0019825 TAS oxygen binding
GO:0020037 IBA:IEA heme binding
GO:0033778 IEA 7alpha-hydroxycholest-4-en-3-one 12alpha-hydroxylase activity
GO:0044281 TAS small molecule metabolic process
GO:0055114 IEA oxidation-reduction process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000053068 cyp8b1 cytochrome P450, family 8, subfamily B, polypeptide 1 protein_coding Danio_rerio
ENSDARG00000097556 cyp8b2 cytochrome P450, family 8, subfamily B, polypeptide 2 protein_coding Danio_rerio
ENSDARG00000097559 cyp8b3 cytochrome P450, family 8, subfamily B, polypeptide 3 protein_coding Danio_rerio
ENSMUSG00000050445 Cyp8b1 cytochrome P450, family 8, subfamily b, polypeptide 1 protein_coding Mus_musculus

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