C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: potassium voltage-gated channel, Isk-related family, member 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000180509 KCNE1 9606 - 21:34446688-34512275 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000337385 KCNE1-201 34446688-34511339 protein_coding
  ENST00000399284 KCNE1-005 34449245-34511243 protein_coding
  ENST00000399286 KCNE1-002 34449056-34512275 protein_coding
  ENST00000399289 KCNE1-001 34446690-34459604 protein_coding
  ENST00000416357 KCNE1-003 34449245-34455741 protein_coding
  ENST00000432085 KCNE1-202 34446688-34459604 protein_coding
  ENST00000489175 KCNE1-004 34509456-34512207 processed_transcript
  ENST00000611936 KCNE1-203 34446688-34511325 protein_coding
  ENST00000621601 KCNE1-204 34446688-34459938 protein_coding

Homo sapiens EnsemblGRCh38

Genome
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Genes
Gene structures from Ensembl
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Transcripts
Structures from Ensembl
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Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000399284ENST00000399286ENST00000489175ENST00000611936
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000399284 N/A N/A 0.536±0.00 N/A N/A N/A 0.175±0.00 N/A N/A 0.611±0.00 N/A 0.140±0.00 0.314±0.15 N/A
ENST00000399286 N/A N/A 0.279±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.303±0.00
ENST00000489175 0.275±0.00 0.533±0.00 0.122±0.00 0.026±0.00 0.249±0.06 0.222±0.14 0.082±0.06 0.461±0.00 0.527±0.42 0.595±0.14 0.017±0.00 0.101±0.06 0.179±0.11 0.229±0.00
ENST00000611936 N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.145±0.00 N/A 0.012±0.00 0.029±0.01 N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008ON CIL_0008ON_0001 VISTA 21:34142879-34745057
CIL_0007SX CIL_0007SX_0001 VISTA 21:34145397-34749042
CIL_0008OM CIL_0008OM_0001 VISTA 21:34146393-34747421
CIL_0008ZS CIL_0008ZS_0001 VISTA 21:34243666-34847364
CIL_00094R CIL_00094R_0001 VISTA 21:34258399-34859715
CIL_00078G CIL_00078G_0001 CGP 21:34446688-34615142

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005249 IDA:IEA voltage-gated potassium channel activity
GO:0005251 IDA delayed rectifier potassium channel activity
GO:0005515 IPI protein binding
GO:0005764 IDA lysosome
GO:0005886 IDA plasma membrane
GO:0006487 IDA protein N-linked glycosylation
GO:0006493 IDA protein O-linked glycosylation
GO:0006811 IEA ion transport
GO:0007605 TAS sensory perception of sound
GO:0008076 IDA voltage-gated potassium channel complex
GO:0009986 IDA cell surface
GO:0015459 IDA potassium channel regulator activity
GO:0016020 IEA membrane
GO:0030018 ISS Z disc
GO:0031433 IPI telethonin binding
GO:0060307 IMP regulation of ventricular cardiac muscle cell membrane repolarization
GO:0071320 IDA cellular response to cAMP
GO:0071435 IDA potassium ion export
GO:0071805 IDA potassium ion transmembrane transport
GO:0086002 IMP cardiac muscle cell action potential involved in contraction
GO:0086005 IMP ventricular cardiac muscle cell action potential
GO:0086008 IDA voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization
GO:0086009 IDA membrane repolarization
GO:0086011 IDA membrane repolarization during action potential
GO:0086013 IMP membrane repolarization during cardiac muscle cell action potential
GO:0086091 IMP regulation of heart rate by cardiac conduction
GO:1901379 IDA regulation of potassium ion transmembrane transport
GO:1901381 IDA positive regulation of potassium ion transmembrane transport
GO:1902259 IDA regulation of delayed rectifier potassium channel activity
GO:1902282 IMP voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000087204 AL807829.1 Uncharacterized protein protein_coding Danio_rerio
ENSMUSG00000039639 Kcne1 potassium voltage-gated channel, Isk-related subfamily, member 1 protein_coding Mus_musculus

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