C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: apoptosis enhancing nuclease
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000181026 AEN 9606 + 15:88621296-88632282 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000332810 AEN-001 88621296-88632282 protein_coding
  ENST00000557787 AEN-003 88621337-88627341 retained_intron
  ENST00000557927 AEN-002 88626612-88632281 retained_intron
  ENST00000558327 AEN-006 88621381-88626611 retained_intron
  ENST00000559528 AEN-004 88621370-88626746 protein_coding
  ENST00000560174 AEN-005 88621381-88626179 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000332810ENST00000557927
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000332810 3.398±0.00 8.950±0.00 0.399±0.00 2.078±0.00 2.049±1.02 5.762±0.00 0.886±0.46 2.189±2.06 2.234±1.12 7.013±6.55 7.288±0.00 5.119±3.38 6.264±1.07 9.571±0.30
ENST00000557927 N/A 0.602±0.00 0.057±0.00 0.146±0.03 0.511±0.00 0.143±0.00 N/A 0.278±0.00 0.112±0.00 0.445±0.00 N/A 0.653±0.00 N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00011E CIL_00011E_0001 CGP 15:88511559-88632282
CIL_00011F CIL_00011F_0001 CGP 15:88621296-88656483

Gene Ontology
GO IDEvidence TypeGO Description
GO:0003676 IEA nucleic acid binding
GO:0004527 IDA:IEA exonuclease activity
GO:0005634 IDA nucleus
GO:0005654 IDA nucleoplasm
GO:0005730 IDA nucleolus
GO:0010212 IDA response to ionizing radiation
GO:0031965 IDA nuclear membrane
GO:0042771 IDA intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
GO:0090305 IEA nucleic acid phosphodiester bond hydrolysis

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000077968 isg20l2 interferon stimulated exonuclease gene 20-like 2 protein_coding Danio_rerio
ENSMUSG00000030609 Aen apoptosis enhancing nuclease protein_coding Mus_musculus

Loading