C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: apoptosis enhancing nuclease
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000030609 Aen 10090 + 7:78895854-78911209 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000107421 Aen-002 78895934-78908374 protein_coding
  ENSMUST00000107423 Aen-003 78896009-78908378 protein_coding
  ENSMUST00000107425 Aen-001 78895927-78909140 protein_coding
  ENSMUST00000123824 Aen-004 78895854-78911209 processed_transcript
  ENSMUST00000138167 Aen-005 78898031-78902822 protein_coding
  ENSMUST00000172017 Aen-006 78895951-78899699 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000107421ENSMUST00000107423ENSMUST00000107425ENSMUST00000123824ENSMUST00000172017
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000107421 12.668±1.19 9.867±0.91 9.723±0.73 7.198±2.04 7.283±1.30 9.581±1.17 9.150±0.45 8.174±0.37 9.791±2.00 6.457±1.05 19.069±0.54 12.567±2.07 13.964±9.54 3.562±1.00
ENSMUST00000107423 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 1.193±0.00
ENSMUST00000107425 2.295±0.41 N/A 1.526±0.30 1.710±0.11 3.331±1.17 2.663±0.34 1.474±0.19 1.487±0.41 1.296±0.43 2.672±0.14 N/A 5.571±1.95 1.307±0.03 0.764±0.16
ENSMUST00000123824 0.838±0.00 2.349±0.35 1.867±0.37 1.948±0.16 1.324±0.09 1.260±0.20 1.453±0.12 0.947±0.10 1.556±0.47 1.401±0.24 2.444±0.31 2.628±0.61 1.152±0.05 0.601±0.20
ENSMUST00000172017 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 24.665±0.00 N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00011E CIL_00011E_0002 CGP 7:78822962-78911209
CIL_00011F CIL_00011F_0002 CGP 7:78895854-78920362

Gene Ontology
GO IDEvidence TypeGO Description
GO:0003676 IEA nucleic acid binding
GO:0004527 ISS exonuclease activity
GO:0005634 IEA nucleus
GO:0005654 ISS nucleoplasm
GO:0005730 ISS nucleolus
GO:0010212 ISS response to ionizing radiation
GO:0031965 IEA nuclear membrane
GO:0042771 ISS intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
GO:0090305 IEA nucleic acid phosphodiester bond hydrolysis

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000077968 isg20l2 interferon stimulated exonuclease gene 20-like 2 protein_coding Danio_rerio
ENSG00000181026 AEN apoptosis enhancing nuclease protein_coding Homo_sapiens

Loading