C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: polymerase (RNA) II (DNA directed) polypeptide A, 220kDa
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000181222 POLR2A 9606 + 17:7484366-7514618 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000572844 POLR2A-002 7484620-7499758 protein_coding
  ENST00000573603 POLR2A-009 7508471-7509927 retained_intron
  ENST00000574158 POLR2A-011 7503401-7503956 retained_intron
  ENST00000575547 POLR2A-006 7498826-7500791 retained_intron
  ENST00000576114 POLR2A-008 7502085-7502724 retained_intron
  ENST00000576553 POLR2A-010 7511515-7512481 retained_intron
  ENST00000576718 POLR2A-007 7502921-7503655 retained_intron
  ENST00000576952 POLR2A-005 7497781-7498519 retained_intron
  ENST00000617998 POLR2A-001 7484366-7514616 protein_coding
  ENST00000621442 POLR2A-201 7484379-7514618 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000617998ENST00000621442
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000617998 4.035±0.00 14.149±0.00 4.934±0.00 40.221±0.00 12.208±11.50 5.174±0.00 12.590±0.00 30.761±0.00 8.886±0.00 20.401±0.00 14.811±0.00 14.701±0.70 9.487±0.07 50.525±0.00
ENST00000621442 27.039±0.00 3.474±0.00 N/A 1.541±0.00 2.021±1.30 5.137±0.00 0.698±0.00 N/A 2.277±0.00 2.969±0.00 2.511±0.30 16.249±8.20 9.647±0.09 38.301±11.09

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000398 TAS mRNA splicing, via spliceosome
GO:0000974 IDA Prp19 complex
GO:0001055 IBA RNA polymerase II activity
GO:0001172 IEA transcription, RNA-templated
GO:0003677 NAS:IEA DNA binding
GO:0003899 NAS:IEA DNA-directed RNA polymerase activity
GO:0003968 IEA RNA-directed RNA polymerase activity
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005654 TAS nucleoplasm
GO:0005665 IDA DNA-directed RNA polymerase II, core complex
GO:0006281 TAS DNA repair
GO:0006283 TAS transcription-coupled nucleotide-excision repair
GO:0006289 TAS nucleotide-excision repair
GO:0006351 IEA transcription, DNA-templated
GO:0006355 NAS regulation of transcription, DNA-templated
GO:0006366 NAS transcription from RNA polymerase II promoter
GO:0006367 TAS transcription initiation from RNA polymerase II promoter
GO:0006368 TAS transcription elongation from RNA polymerase II promoter
GO:0006370 TAS 7-methylguanosine mRNA capping
GO:0008380 TAS RNA splicing
GO:0010467 TAS gene expression
GO:0016032 TAS viral process
GO:0031625 IPI ubiquitin protein ligase binding
GO:0033120 IDA positive regulation of RNA splicing
GO:0044822 IDA poly(A) RNA binding
GO:0046872 IEA metal ion binding
GO:0050434 TAS positive regulation of viral transcription

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000076177 polr2a polymerase (RNA) II (DNA directed) polypeptide A protein_coding Danio_rerio
ENSMUSG00000005198 Polr2a polymerase (RNA) II (DNA directed) polypeptide A protein_coding Mus_musculus

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