Warning (512): _cake_core_ cache was unable to write 'cake_dev_eng' to File cache [CORE/Cake/Cache/Cache.php, line 323]
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$success = false
Cache::write() - CORE/Cake/Cache/Cache.php, line 323
I18n::translate() - CORE/Cake/I18n/I18n.php, line 237
__d - CORE/Cake/basics.php, line 617
Cache::write() - CORE/Cake/Cache/Cache.php, line 321
DataSource::listSources() - CORE/Cake/Model/Datasource/DataSource.php, line 110
Mysql::listSources() - CORE/Cake/Model/Datasource/Database/Mysql.php, line 219
Model::setSource() - CORE/Cake/Model/Model.php, line 1142
Model::getDataSource() - CORE/Cake/Model/Model.php, line 3551
Model::__call() - CORE/Cake/Model/Model.php, line 808
Transcript::findByid() - APP/Controller/TranscriptController.php, line 319
TranscriptController::show() - APP/Controller/TranscriptController.php, line 319
ReflectionMethod::invokeArgs() - [internal], line ??
Controller::invokeAction() - CORE/Cake/Controller/Controller.php, line 490
Dispatcher::_invoke() - CORE/Cake/Routing/Dispatcher.php, line 191
Dispatcher::dispatch() - CORE/Cake/Routing/Dispatcher.php, line 165
[main] - APP/webroot/index.php, line 108

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Cache::write() - CORE/Cake/Cache/Cache.php, line 323
DataSource::listSources() - CORE/Cake/Model/Datasource/DataSource.php, line 110
Mysql::listSources() - CORE/Cake/Model/Datasource/Database/Mysql.php, line 219
Model::setSource() - CORE/Cake/Model/Model.php, line 1142
Model::getDataSource() - CORE/Cake/Model/Model.php, line 3551
Model::__call() - CORE/Cake/Model/Model.php, line 808
Transcript::findByid() - APP/Controller/TranscriptController.php, line 319
TranscriptController::show() - APP/Controller/TranscriptController.php, line 319
ReflectionMethod::invokeArgs() - [internal], line ??
Controller::invokeAction() - CORE/Cake/Controller/Controller.php, line 490
Dispatcher::_invoke() - CORE/Cake/Routing/Dispatcher.php, line 191
Dispatcher::dispatch() - CORE/Cake/Routing/Dispatcher.php, line 165
[main] - APP/webroot/index.php, line 108

Warning (512): _cake_model_ cache was unable to write 'default_citloci_list' to File cache [CORE/Cake/Cache/Cache.php, line 323]
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Cache::write() - CORE/Cake/Cache/Cache.php, line 323
DataSource::listSources() - CORE/Cake/Model/Datasource/DataSource.php, line 110
Mysql::listSources() - CORE/Cake/Model/Datasource/Database/Mysql.php, line 236
Model::setSource() - CORE/Cake/Model/Model.php, line 1142
Model::getDataSource() - CORE/Cake/Model/Model.php, line 3551
Model::__call() - CORE/Cake/Model/Model.php, line 808
Transcript::findByid() - APP/Controller/TranscriptController.php, line 319
TranscriptController::show() - APP/Controller/TranscriptController.php, line 319
ReflectionMethod::invokeArgs() - [internal], line ??
Controller::invokeAction() - CORE/Cake/Controller/Controller.php, line 490
Dispatcher::_invoke() - CORE/Cake/Routing/Dispatcher.php, line 191
Dispatcher::dispatch() - CORE/Cake/Routing/Dispatcher.php, line 165
[main] - APP/webroot/index.php, line 108

Warning (512): _cake_model_ cache was unable to write 'default_citloci_transcripts' to File cache [CORE/Cake/Cache/Cache.php, line 323]
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                ),
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Cache::write() - CORE/Cake/Cache/Cache.php, line 323
DataSource::_cacheDescription() - CORE/Cake/Model/Datasource/DataSource.php, line 310
DataSource::describe() - CORE/Cake/Model/Datasource/DataSource.php, line 135
Mysql::describe() - CORE/Cake/Model/Datasource/Database/Mysql.php, line 332
Model::schema() - CORE/Cake/Model/Model.php, line 1372
DboSource::fields() - CORE/Cake/Model/Datasource/DboSource.php, line 2491
DboSource::read() - CORE/Cake/Model/Datasource/DboSource.php, line 1054
Model::_readDataSource() - CORE/Cake/Model/Model.php, line 2947
Model::find() - CORE/Cake/Model/Model.php, line 2919
DboSource::query() - CORE/Cake/Model/Datasource/DboSource.php, line 597
Model::__call() - CORE/Cake/Model/Model.php, line 808
Transcript::findByid() - APP/Controller/TranscriptController.php, line 319
TranscriptController::show() - APP/Controller/TranscriptController.php, line 319
ReflectionMethod::invokeArgs() - [internal], line ??
Controller::invokeAction() - CORE/Cake/Controller/Controller.php, line 490
Dispatcher::_invoke() - CORE/Cake/Routing/Dispatcher.php, line 191
Dispatcher::dispatch() - CORE/Cake/Routing/Dispatcher.php, line 165

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DataSource::_cacheDescription() - CORE/Cake/Model/Datasource/DataSource.php, line 310
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Model::_readDataSource() - CORE/Cake/Model/Model.php, line 2947
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ReflectionMethod::invokeArgs() - [internal], line ??
Controller::invokeAction() - CORE/Cake/Controller/Controller.php, line 490
Dispatcher::_invoke() - CORE/Cake/Routing/Dispatcher.php, line 191
Dispatcher::dispatch() - CORE/Cake/Routing/Dispatcher.php, line 165
[main] - APP/webroot/index.php, line 108

C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

• HOME
• REGIONS
• GENES
• TRANSCRIPTS
• HELP
• CONTACT

Transcript Info
Description:	polymerase (RNA) II (DNA directed) polypeptide A, 220kDa
Transcript Accession	Transcript Name	Contained in Gene	Tax ID	Strand	Position	Biotype
ENST00000572844	POLR2A-002	ENSG00000181222	9606	+	17:7484620-7499758	protein_coding

Expression Patterns No expression data.

Conserved Regions
Gene is not located within a conserved region.

Gene Ontology
GO ID	Evidence Type	GO Description
GO:0000398	TAS	mRNA splicing, via spliceosome
GO:0000974	IDA	Prp19 complex
GO:0001055	IBA	RNA polymerase II activity
GO:0001172	IEA	transcription, RNA-templated
GO:0003677	NAS:IEA	DNA binding
GO:0003899	NAS:IEA	DNA-directed RNA polymerase activity
GO:0003968	IEA	RNA-directed RNA polymerase activity
GO:0005515	IPI	protein binding
GO:0005634	IDA	nucleus
GO:0005654	TAS	nucleoplasm
GO:0005665	IDA	DNA-directed RNA polymerase II, core complex
GO:0006281	TAS	DNA repair
GO:0006283	TAS	transcription-coupled nucleotide-excision repair
GO:0006289	TAS	nucleotide-excision repair
GO:0006351	IEA	transcription, DNA-templated
GO:0006355	NAS	regulation of transcription, DNA-templated
GO:0006366	NAS	transcription from RNA polymerase II promoter
GO:0006367	TAS	transcription initiation from RNA polymerase II promoter
GO:0006368	TAS	transcription elongation from RNA polymerase II promoter
GO:0006370	TAS	7-methylguanosine mRNA capping
GO:0008380	TAS	RNA splicing
GO:0010467	TAS	gene expression
GO:0016032	TAS	viral process
GO:0031625	IPI	ubiquitin protein ligase binding
GO:0033120	IDA	positive regulation of RNA splicing
GO:0044822	IDA	poly(A) RNA binding
GO:0046872	IEA	metal ion binding
GO:0050434	TAS	positive regulation of viral transcription

Homologs
ENSEMBL Accession	Gene Name	Biotype	Species	E-Value	Bit Score
ENSMUST00000058470	Polr2a-001	protein_coding	Mus_musculus	0	2425
ENSMUST00000071213	Polr2a-201	protein_coding	Mus_musculus	0	2257
ENSDART00000077495	polr2a-001	protein_coding	Danio_rerio	0	1194

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Cache::write() - CORE/Cake/Cache/Cache.php, line 323
App::shutdown() - CORE/Cake/Core/App.php, line 899
[main] - [internal], line ??

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			(int) 6 => '`Transcript`.`strand`',
			(int) 7 => '`Transcript`.`start`',
			(int) 8 => '`Transcript`.`end`',
			(int) 9 => '`Transcript`.`transcript_name`',
			(int) 10 => '`Transcript`.`transcript_source`',
			(int) 11 => '`Transcript`.`transcript_biotype`',
			(int) 12 => '`Transcript`.`annotation_version`'
		)
	)
)
$config = '_cake_core_'
$settings = array(
	'prefix' => '*****',
	'engine' => 'File',
	'path' => '/var/www/c-it-loci/app/tmp/cache/persistent/',
	'serialize' => true,
	'duration' => (int) 10,
	'lock' => true,
	'isWindows' => false,
	'mask' => (int) 436,
	'probability' => (int) 100,
	'groups' => array()
)
$success = false
Cache::write() - CORE/Cake/Cache/Cache.php, line 323
DboSource::__destruct() - CORE/Cake/Model/Datasource/DboSource.php, line 3539
[main] - [internal], line ??