C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: apoptosis-associated tyrosine kinase
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000181409 AATK 9606 - 17:81117295-81166077 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000326724 AATK-001 81117295-81166017 protein_coding
  ENST00000374792 AATK-004 81117298-81166072 nonsense_mediated_decay
  ENST00000417379 AATK-002 81117304-81131948 protein_coding
  ENST00000570932 AATK-003 81117298-81121505 nonsense_mediated_decay
  ENST00000572339 AATK-008 81124962-81128888 processed_transcript
  ENST00000572798 AATK-005 81134368-81166077 processed_transcript
  ENST00000573441 AATK-010 81122509-81125014 processed_transcript
  ENST00000573469 AATK-009 81118000-81128900 retained_intron
  ENST00000575363 AATK-006 81127853-81132847 protein_coding
  ENST00000576053 AATK-007 81126446-81128925 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeBrainHeartLungENST00000326724ENST00000417379
Transcript ID Adipose Brain Heart Lung
ENST00000326724 7.116±0.00 N/A N/A N/A
ENST00000417379 N/A 21.524±15.24 1.402±0.00 4.949±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0003UC CIL_0003UC_0002 CGP 17:80991598-81117432
CIL_0003U3 CIL_0003U3_0002 CGP 17:81035122-81166077
CIL_00042H CIL_00042H_0001 CGP 17:81117295-81222999

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004672 IEA protein kinase activity
GO:0004674 IEA protein serine/threonine kinase activity
GO:0004713 IEA protein tyrosine kinase activity
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0005783 IEA endoplasmic reticulum
GO:0006468 IEA protein phosphorylation
GO:0006915 IEA apoptotic process
GO:0007420 IEA brain development
GO:0016021 IEA integral component of membrane
GO:0016772 IEA transferase activity, transferring phosphorus-containing groups
GO:0030517 IEA negative regulation of axon extension
GO:0032482 IEA Rab protein signal transduction
GO:0038083 IEA peptidyl-tyrosine autophosphorylation
GO:0044295 IEA axonal growth cone
GO:0046777 IEA protein autophosphorylation
GO:0048471 IEA perinuclear region of cytoplasm
GO:0051402 IEA neuron apoptotic process
GO:0055037 IEA recycling endosome

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000077477 aatkb apoptosis-associated tyrosine kinase b protein_coding Danio_rerio
ENSDARG00000078222 aatka apoptosis-associated tyrosine kinase a protein_coding Danio_rerio
ENSMUSG00000025375 Aatk apoptosis-associated tyrosine kinase protein_coding Mus_musculus

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