C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: apoptosis-associated tyrosine kinase
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000025375 Aatk 10090 - 11:120007313-120047167 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000064307 Aatk-002 120007313-120047070 protein_coding
  ENSMUST00000103019 Aatk-003 120007320-120041782 protein_coding
  ENSMUST00000103020 Aatk-001 120007320-120047145 protein_coding
  ENSMUST00000128836 Aatk-009 120015392-120016872 processed_transcript
  ENSMUST00000132575 Aatk-007 120013690-120017156 processed_transcript
  ENSMUST00000134319 Aatk-006 120016738-120020168 processed_transcript
  ENSMUST00000136386 Aatk-008 120012395-120016897 processed_transcript
  ENSMUST00000142959 Aatk-005 120007313-120012408 processed_transcript
  ENSMUST00000150730 Aatk-004 120007313-120047167 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000064307ENSMUST00000103019ENSMUST00000103020ENSMUST00000142959ENSMUST00000150730
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000064307 0.658±0.00 2.562±1.69 1.329±0.00 11.779±5.85 N/A 0.940±0.50 0.455±0.00 0.344±0.07 0.212±0.17 N/A 0.635±0.00 0.899±0.28 0.356±0.30 0.138±0.04
ENSMUST00000103019 3.486±1.31 1.778±0.44 0.974±0.12 13.978±0.00 4.984±2.48 0.983±0.22 0.357±0.04 0.427±0.07 0.228±0.14 1.946±0.41 0.844±0.38 1.494±0.00 0.239±0.13 0.046±0.00
ENSMUST00000103020 N/A 2.568±0.45 0.769±0.00 6.632±0.43 N/A 1.209±0.42 0.395±0.15 0.345±0.14 N/A 2.402±0.41 0.247±0.01 0.771±0.20 N/A 0.040±0.00
ENSMUST00000142959 5.508±3.40 5.555±1.90 1.304±0.00 8.566±1.30 6.561±0.65 1.914±0.56 1.285±0.45 0.823±0.21 0.174±0.08 3.040±0.71 0.664±0.21 1.391±0.75 0.245±0.10 0.125±0.02
ENSMUST00000150730 N/A N/A 0.498±0.00 1.720±0.00 N/A N/A N/A N/A 0.195±0.00 N/A N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0003U3 CIL_0003U3_0003 CGP 11:119942763-120047167
CIL_00042H CIL_00042H_0002 CGP 11:120007313-120086827

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004713 IDA protein tyrosine kinase activity
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0005783 IDA endoplasmic reticulum
GO:0006915 IDA apoptotic process
GO:0007420 IMP brain development
GO:0030517 IGI negative regulation of axon extension
GO:0032482 IGI Rab protein signal transduction
GO:0038083 IDA peptidyl-tyrosine autophosphorylation
GO:0044295 IDA axonal growth cone
GO:0046777 IDA protein autophosphorylation
GO:0048471 IDA perinuclear region of cytoplasm
GO:0051402 IDA neuron apoptotic process
GO:0055037 IDA recycling endosome

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000077477 aatkb apoptosis-associated tyrosine kinase b protein_coding Danio_rerio
ENSDARG00000078222 aatka apoptosis-associated tyrosine kinase a protein_coding Danio_rerio
ENSG00000181409 AATK apoptosis-associated tyrosine kinase protein_coding Homo_sapiens

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