C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: FES proto-oncogene, tyrosine kinase
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000182511 FES 9606 + 15:90883695-90895776 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000328850 FES-001 90884412-90895776 protein_coding
  ENST00000394300 FES-005 90885046-90895565 protein_coding
  ENST00000394302 FES-006 90884469-90895560 protein_coding
  ENST00000414248 FES-017 90884447-90895693 protein_coding
  ENST00000416779 FES-007 90883695-90885172 protein_coding
  ENST00000443697 FES-011 90884713-90885542 protein_coding
  ENST00000444422 FES-018 90885046-90895565 protein_coding
  ENST00000448367 FES-014 90889550-90891022 processed_transcript
  ENST00000452243 FES-010 90884504-90887015 protein_coding
  ENST00000462476 FES-015 90889849-90890525 retained_intron
  ENST00000464684 FES-003 90884523-90895598 nonsense_mediated_decay
  ENST00000470152 FES-019 90884447-90889378 nonsense_mediated_decay
  ENST00000481665 FES-009 90884469-90885529 retained_intron
  ENST00000494259 FES-013 90889206-90889939 retained_intron
  ENST00000496379 FES-016 90889840-90892409 retained_intron
  ENST00000497945 FES-012 90885340-90889325 retained_intron
  ENST00000559355 FES-020 90884469-90887209 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000328850ENST00000394300ENST00000394302ENST00000414248ENST00000443697ENST00000444422ENST00000462476ENST00000470152ENST00000496379ENST00000497945ENST00000559355
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000328850 8.067±0.00 8.053±0.00 N/A 0.852±0.73 3.019±0.00 3.565±0.00 2.316±0.00 6.045±0.00 2.056±0.00 11.661±0.00 N/A 4.393±1.19 9.000±6.59 3.418±2.87
ENST00000394300 4.496±0.00 5.643±0.00 N/A N/A 3.901±0.00 N/A 0.516±0.21 N/A 1.049±0.06 0.520±0.00 1.467±0.00 2.143±1.07 3.669±0.00 1.601±0.00
ENST00000394302 N/A N/A 0.363±0.00 N/A N/A N/A N/A 1.115±0.00 N/A N/A N/A N/A N/A N/A
ENST00000414248 N/A N/A N/A N/A N/A 1.004±0.00 N/A N/A N/A N/A N/A N/A 2.576±0.00 0.602±0.00
ENST00000443697 N/A N/A N/A N/A N/A 0.843±0.00 N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000444422 N/A N/A N/A N/A 0.784±0.00 1.197±0.81 N/A N/A 0.531±0.00 1.254±0.00 N/A 2.473±1.31 3.740±1.13 0.896±0.00
ENST00000462476 N/A N/A N/A 0.635±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000470152 N/A N/A N/A N/A N/A N/A N/A N/A N/A 1.317±0.00 N/A N/A N/A N/A
ENST00000496379 N/A N/A N/A 0.446±0.00 N/A N/A 0.905±0.00 N/A N/A N/A N/A N/A N/A N/A
ENST00000497945 N/A N/A N/A N/A N/A N/A N/A 4.588±0.00 N/A N/A N/A N/A N/A N/A
ENST00000559355 N/A N/A N/A N/A N/A N/A N/A 2.476±0.00 N/A N/A N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008AY CIL_0008AY_0001 VISTA 15:90522657-91123707
CIL_00077N CIL_00077N_0002 CGP 15:90868592-90895776

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004672 IEA protein kinase activity
GO:0004713 IDA:IEA protein tyrosine kinase activity
GO:0004715 IDA non-membrane spanning protein tyrosine kinase activity
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0005737 IDA cytoplasm
GO:0005794 IEA Golgi apparatus
GO:0005829 TAS cytosol
GO:0005856 IEA cytoskeleton
GO:0005925 IDA focal adhesion
GO:0006468 TAS:IEA protein phosphorylation
GO:0007275 TAS multicellular organismal development
GO:0007411 TAS axon guidance
GO:0008283 TAS cell proliferation
GO:0008360 IMP regulation of cell shape
GO:0010976 IMP positive regulation of neuron projection development
GO:0015630 IDA microtubule cytoskeleton
GO:0016020 IEA membrane
GO:0016192 IEA vesicle-mediated transport
GO:0016772 IEA transferase activity, transferring phosphorus-containing groups
GO:0018108 IDA:IEA peptidyl-tyrosine phosphorylation
GO:0030155 IMP regulation of cell adhesion
GO:0031116 IMP positive regulation of microtubule polymerization
GO:0031234 IDA extrinsic component of cytoplasmic side of plasma membrane
GO:0031410 IDA cytoplasmic vesicle
GO:0034987 IDA immunoglobulin receptor binding
GO:0035091 IDA phosphatidylinositol binding
GO:0042127 IMP regulation of cell proliferation
GO:0043304 IMP regulation of mast cell degranulation
GO:0045595 IMP regulation of cell differentiation
GO:0045639 IMP positive regulation of myeloid cell differentiation
GO:0046777 IDA protein autophosphorylation
GO:0060627 TAS regulation of vesicle-mediated transport
GO:2000145 IMP regulation of cell motility
GO:2000251 IMP positive regulation of actin cytoskeleton reorganization

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000011449 fes feline sarcoma oncogene protein_coding Danio_rerio
ENSMUSG00000053158 Fes feline sarcoma oncogene protein_coding Mus_musculus

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