C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: FES proto-oncogene, tyrosine kinase
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000444422 FES-018 ENSG00000182511 9606 + 15:90885046-90895565 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BreastColonLiverLungOvaryPlacentaTestisENST00000444422
Transcript ID Breast Colon Liver Lung Ovary Placenta Testis
ENST00000444422 0.784±0.00 1.197±0.81 0.531±0.00 1.254±0.00 2.473±1.31 3.740±1.13 0.896±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008AY CIL_0008AY_0001 VISTA 15:90522657-91123707
CIL_00077N CIL_00077N_0002 CGP 15:90868592-90895776

Gene Ontology

GO IDEvidence TypeGO Description
GO:0004672 IEA protein kinase activity
GO:0004713 IDA:IEA protein tyrosine kinase activity
GO:0004715 IDA non-membrane spanning protein tyrosine kinase activity
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0005737 IDA cytoplasm
GO:0005794 IEA Golgi apparatus
GO:0005829 TAS cytosol
GO:0005925 IDA focal adhesion
GO:0006468 TAS:IEA protein phosphorylation
GO:0007275 TAS multicellular organismal development
GO:0007411 TAS axon guidance
GO:0008283 TAS cell proliferation
GO:0008360 IMP regulation of cell shape
GO:0010976 IMP positive regulation of neuron projection development
GO:0015630 IDA microtubule cytoskeleton
GO:0016020 IEA membrane
GO:0016192 IEA vesicle-mediated transport
GO:0016772 IEA transferase activity, transferring phosphorus-containing groups
GO:0018108 IDA:IEA peptidyl-tyrosine phosphorylation
GO:0030155 IMP regulation of cell adhesion
GO:0031116 IMP positive regulation of microtubule polymerization
GO:0031234 IDA extrinsic component of cytoplasmic side of plasma membrane
GO:0031410 IDA cytoplasmic vesicle
GO:0034987 IDA immunoglobulin receptor binding
GO:0035091 IDA phosphatidylinositol binding
GO:0042127 IMP regulation of cell proliferation
GO:0043304 IMP regulation of mast cell degranulation
GO:0045595 IMP regulation of cell differentiation
GO:0045639 IMP positive regulation of myeloid cell differentiation
GO:0046777 IDA protein autophosphorylation
GO:0060627 TAS regulation of vesicle-mediated transport
GO:2000145 IMP regulation of cell motility
GO:2000251 IMP positive regulation of actin cytoskeleton reorganization

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000080932 Fes-201 protein_coding Mus_musculus 0 1434
ENSDART00000050957 fer-201 protein_coding Danio_rerio 1e-29 135
ENSDART00000149855 fer-001 protein_coding Danio_rerio 1e-29 135

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