C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: growth arrest-specific 6
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000183087 GAS6 9606 - 13:113820549-113864067 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000327773 GAS6-001 113820558-113864067 protein_coding
  ENST00000476291 GAS6-003 113847677-113864015 processed_transcript
  ENST00000480426 GAS6-002 113820549-113833741 retained_intron
  ENST00000608763 GAS6-005 113820549-113823194 retained_intron
  ENST00000610073 GAS6-004 113820552-113836044 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000327773ENST00000480426ENST00000610073
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000327773 78.659±0.00 27.525±0.00 2.295±0.00 10.621±5.39 35.621±27.88 40.821±35.09 52.728±45.28 38.958±37.54 17.030±2.22 70.007±61.59 36.741±27.89 86.555±78.32 82.536±12.51 71.065±18.18
ENST00000480426 N/A N/A N/A N/A N/A 1.333±0.00 N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000610073 N/A N/A N/A N/A N/A 1.746±0.00 N/A N/A N/A N/A N/A 12.474±9.98 68.121±0.00 66.197±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0001EE CIL_0001EE_0001 CGP 13:113759240-113864067

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001764 IEA neuron migration
GO:0001786 IDA phosphatidylserine binding
GO:0001934 ISS positive regulation of protein phosphorylation
GO:0001961 IMP positive regulation of cytokine-mediated signaling pathway
GO:0002576 TAS platelet degranulation
GO:0003104 ISS positive regulation of glomerular filtration
GO:0005102 IDA receptor binding
GO:0005245 IDA voltage-gated calcium channel activity
GO:0005509 IEA calcium ion binding
GO:0005515 IPI:IEA protein binding
GO:0005576 TAS:IEA extracellular region
GO:0005615 IDA extracellular space
GO:0005622 IEA intracellular
GO:0005737 IDA cytoplasm
GO:0005788 TAS endoplasmic reticulum lumen
GO:0005796 TAS Golgi lumen
GO:0006468 IDA protein phosphorylation
GO:0006508 TAS proteolysis
GO:0006909 IDA phagocytosis
GO:0007050 TAS cell cycle arrest
GO:0007155 TAS cell adhesion
GO:0007165 TAS signal transduction
GO:0007167 IEA enzyme linked receptor protein signaling pathway
GO:0007596 TAS blood coagulation
GO:0008283 TAS cell proliferation
GO:0009267 IEA cellular response to starvation
GO:0010628 IDA positive regulation of gene expression
GO:0010804 IDA negative regulation of tumor necrosis factor-mediated signaling pathway
GO:0010934 IEA macrophage cytokine production
GO:0016477 TAS cell migration
GO:0017187 TAS peptidyl-glutamic acid carboxylation
GO:0018105 IDA peptidyl-serine phosphorylation
GO:0019064 IDA fusion of virus membrane with host plasma membrane
GO:0019079 IDA viral genome replication
GO:0030168 TAS platelet activation
GO:0030296 IDA protein tyrosine kinase activator activity
GO:0030971 IPI receptor tyrosine kinase binding
GO:0031093 TAS platelet alpha granule lumen
GO:0031100 IEA organ regeneration
GO:0031589 IEA cell-substrate adhesion
GO:0032008 ISS positive regulation of TOR signaling
GO:0032148 ISS activation of protein kinase B activity
GO:0032689 IDA negative regulation of interferon-gamma production
GO:0032715 IDA negative regulation of interleukin-6 production
GO:0032720 IDA negative regulation of tumor necrosis factor production
GO:0032825 IDA positive regulation of natural killer cell differentiation
GO:0033138 IDA positive regulation of peptidyl-serine phosphorylation
GO:0033159 IDA negative regulation of protein import into nucleus, translocation
GO:0035457 IDA cellular response to interferon-alpha
GO:0035690 IDA cellular response to drug
GO:0035754 IDA B cell chemotaxis
GO:0040008 IEA regulation of growth
GO:0043027 IDA cysteine-type endopeptidase inhibitor activity involved in apoptotic process
GO:0043066 IDA negative regulation of apoptotic process
GO:0043154 IDA negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0043277 IDA apoptotic cell clearance
GO:0043433 IDA negative regulation of sequence-specific DNA binding transcription factor activity
GO:0043491 IDA protein kinase B signaling
GO:0043687 TAS post-translational protein modification
GO:0044267 TAS cellular protein metabolic process
GO:0045860 IDA positive regulation of protein kinase activity
GO:0045892 IDA negative regulation of transcription, DNA-templated
GO:0046718 IDA viral entry into host cell
GO:0046813 IDA receptor-mediated virion attachment to host cell
GO:0046827 IDA positive regulation of protein export from nucleus
GO:0048018 IDA receptor agonist activity
GO:0048146 IDA positive regulation of fibroblast proliferation
GO:0050711 IDA negative regulation of interleukin-1 secretion
GO:0050766 IDA positive regulation of phagocytosis
GO:0050900 TAS leukocyte migration
GO:0051897 IDA positive regulation of protein kinase B signaling
GO:0060090 IDA binding, bridging
GO:0061098 IDA positive regulation of protein tyrosine kinase activity
GO:0070062 IDA extracellular vesicular exosome
GO:0070168 IDA negative regulation of biomineral tissue development
GO:0070374 IDA positive regulation of ERK1 and ERK2 cascade
GO:0070527 TAS platelet aggregation
GO:0070588 IDA calcium ion transmembrane transport
GO:0071307 IDA cellular response to vitamin K
GO:0071333 ISS cellular response to glucose stimulus
GO:0071363 IEA cellular response to growth factor stimulus
GO:0072661 IDA protein targeting to plasma membrane
GO:0085029 ISS extracellular matrix assembly
GO:0097028 IEP dendritic cell differentiation
GO:0097241 IDA hematopoietic stem cell migration to bone marrow
GO:1900142 IDA negative regulation of oligodendrocyte apoptotic process
GO:1900165 IDA negative regulation of interleukin-6 secretion
GO:2000270 IDA negative regulation of fibroblast apoptotic process
GO:2000352 IDA negative regulation of endothelial cell apoptotic process
GO:2000510 IDA positive regulation of dendritic cell chemotaxis
GO:2000533 ISS negative regulation of renal albumin absorption
GO:2000669 IDA negative regulation of dendritic cell apoptotic process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000007804 gas6 growth arrest-specific 6 protein_coding Danio_rerio
ENSMUSG00000031451 Gas6 growth arrest specific 6 protein_coding Mus_musculus

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