C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: growth arrest specific 6
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000031451 Gas6 10090 - 8:13465374-13494535 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000033828 Gas6-201 13465374-13494535 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000033828
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000033828 145.168±51.84 164.312±61.64 142.579±0.91 17.951±10.14 96.692±32.84 194.456±25.36 58.930±8.76 238.780±14.83 14.349±11.02 146.408±16.85 28.794±3.83 517.721±109.18 12.123±10.50 22.301±6.07

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0001EE CIL_0001EE_0002 CGP 8:13435459-13494535

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001764 IGI neuron migration
GO:0001786 ISS phosphatidylserine binding
GO:0001934 ISS positive regulation of protein phosphorylation
GO:0001961 ISS positive regulation of cytokine-mediated signaling pathway
GO:0003104 ISS positive regulation of glomerular filtration
GO:0005102 ISS receptor binding
GO:0005245 ISS voltage-gated calcium channel activity
GO:0005509 IEA calcium ion binding
GO:0005615 IDA extracellular space
GO:0005622 IEA intracellular
GO:0005737 ISS cytoplasm
GO:0006468 ISS protein phosphorylation
GO:0006909 ISS phagocytosis
GO:0007165 IEA signal transduction
GO:0007167 IGI enzyme linked receptor protein signaling pathway
GO:0007596 IMP blood coagulation
GO:0009267 IDA cellular response to starvation
GO:0010628 ISS positive regulation of gene expression
GO:0010804 ISS negative regulation of tumor necrosis factor-mediated signaling pathway
GO:0010934 IMP macrophage cytokine production
GO:0018105 ISS peptidyl-serine phosphorylation
GO:0019064 ISS fusion of virus membrane with host plasma membrane
GO:0019079 ISS viral genome replication
GO:0030296 ISS protein tyrosine kinase activator activity
GO:0030971 IEA receptor tyrosine kinase binding
GO:0031100 IEA organ regeneration
GO:0031589 IMP cell-substrate adhesion
GO:0032008 ISS positive regulation of TOR signaling
GO:0032148 ISS activation of protein kinase B activity
GO:0032689 ISS negative regulation of interferon-gamma production
GO:0032715 IEA negative regulation of interleukin-6 production
GO:0032720 ISS negative regulation of tumor necrosis factor production
GO:0032825 ISS positive regulation of natural killer cell differentiation
GO:0033138 ISS positive regulation of peptidyl-serine phosphorylation
GO:0033159 ISS negative regulation of protein import into nucleus, translocation
GO:0035457 ISS cellular response to interferon-alpha
GO:0035690 ISS cellular response to drug
GO:0035754 ISS B cell chemotaxis
GO:0040008 IEA regulation of growth
GO:0043027 ISS cysteine-type endopeptidase inhibitor activity involved in apoptotic process
GO:0043066 IMP negative regulation of apoptotic process
GO:0043154 ISS negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0043277 IDA apoptotic cell clearance
GO:0043433 ISS negative regulation of sequence-specific DNA binding transcription factor activity
GO:0043491 IGI protein kinase B signaling
GO:0045860 ISS positive regulation of protein kinase activity
GO:0045892 ISS negative regulation of transcription, DNA-templated
GO:0046718 ISS viral entry into host cell
GO:0046813 ISS receptor-mediated virion attachment to host cell
GO:0046827 ISS positive regulation of protein export from nucleus
GO:0048018 IDA receptor agonist activity
GO:0048146 ISS positive regulation of fibroblast proliferation
GO:0050711 ISS negative regulation of interleukin-1 secretion
GO:0050766 ISS positive regulation of phagocytosis
GO:0051897 ISS positive regulation of protein kinase B signaling
GO:0060090 ISS binding, bridging
GO:0061098 ISS positive regulation of protein tyrosine kinase activity
GO:0070062 IEA extracellular vesicular exosome
GO:0070168 ISS negative regulation of biomineral tissue development
GO:0070374 IEA positive regulation of ERK1 and ERK2 cascade
GO:0070588 IEA calcium ion transmembrane transport
GO:0071307 ISS cellular response to vitamin K
GO:0071333 ISS cellular response to glucose stimulus
GO:0071363 IMP cellular response to growth factor stimulus
GO:0072661 ISS protein targeting to plasma membrane
GO:0085029 ISS extracellular matrix assembly
GO:0097028 IEA dendritic cell differentiation
GO:0097241 ISS hematopoietic stem cell migration to bone marrow
GO:1900142 IEA negative regulation of oligodendrocyte apoptotic process
GO:1900165 ISS negative regulation of interleukin-6 secretion
GO:2000270 ISS negative regulation of fibroblast apoptotic process
GO:2000352 ISS negative regulation of endothelial cell apoptotic process
GO:2000510 IEA positive regulation of dendritic cell chemotaxis
GO:2000533 ISS negative regulation of renal albumin absorption
GO:2000669 ISS negative regulation of dendritic cell apoptotic process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000007804 gas6 growth arrest-specific 6 protein_coding Danio_rerio
ENSG00000183087 GAS6 growth arrest-specific 6 protein_coding Homo_sapiens

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