C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: MX dynamin-like GTPase 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000183486 MX2 9606 + 21:41361943-41409390 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000330714 MX2-001 41361943-41408943 protein_coding
  ENST00000398632 MX2-005 41402634-41408943 retained_intron
  ENST00000416447 MX2-009 41370213-41376949 protein_coding
  ENST00000418103 MX2-008 41370514-41377940 protein_coding
  ENST00000435611 MX2-007 41362007-41377916 protein_coding
  ENST00000436410 MX2-006 41361999-41377927 protein_coding
  ENST00000474368 MX2-004 41400865-41404873 retained_intron
  ENST00000481838 MX2-003 41398985-41408026 processed_transcript
  ENST00000482953 MX2-002 41389543-41409390 retained_intron
  ENST00000493753 MX2-012 41397631-41399766 retained_intron
  ENST00000494252 MX2-010 41362027-41364666 processed_transcript
  ENST00000495892 MX2-013 41362030-41367306 retained_intron
  ENST00000496774 MX2-011 41390651-41402200 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000330714ENST00000398632ENST00000418103ENST00000435611ENST00000474368ENST00000481838ENST00000482953ENST00000493753ENST00000495892ENST00000496774
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000330714 6.995±0.00 6.169±0.00 N/A 0.717±0.00 3.500±0.33 1.580±1.44 1.841±0.62 0.399±0.00 0.619±0.32 3.134±0.29 0.391±0.00 3.258±0.98 4.274±1.00 1.649±1.39
ENST00000398632 N/A N/A N/A 0.185±0.00 N/A N/A N/A N/A N/A N/A 0.204±0.00 N/A N/A N/A
ENST00000418103 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 1.307±0.00
ENST00000435611 N/A N/A N/A 0.462±0.00 N/A N/A N/A 2.053±0.00 N/A N/A N/A 4.622±0.00 N/A N/A
ENST00000474368 N/A N/A 0.063±0.00 N/A 1.774±0.00 N/A N/A N/A N/A 0.643±0.00 N/A N/A N/A N/A
ENST00000481838 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.600±0.00 N/A N/A N/A
ENST00000482953 N/A 1.859±0.00 N/A N/A 0.702±0.00 N/A N/A N/A N/A N/A N/A 0.894±0.00 N/A N/A
ENST00000493753 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 1.366±0.00
ENST00000495892 N/A N/A N/A 0.022±0.00 N/A 0.192±0.00 N/A 0.225±0.00 N/A 1.417±0.00 N/A N/A N/A N/A
ENST00000496774 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 4.619±0.00 N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0001CV CIL_0001CV_0004 CGP 21:41361943-41459214

Gene Ontology

GO IDEvidence TypeGO Description
GO:0003924 IEA GTPase activity
GO:0005515 IEA protein binding
GO:0005525 IMP:IEA GTP binding
GO:0005634 TAS nucleus
GO:0005643 IDA nuclear pore
GO:0005737 TAS cytoplasm
GO:0005829 TAS cytosol
GO:0006184 IEA GTP catabolic process
GO:0006952 TAS defense response
GO:0009615 IDA response to virus
GO:0015031 IEA protein transport
GO:0019221 TAS cytokine-mediated signaling pathway
GO:0035455 IDA response to interferon-alpha
GO:0046822 IMP regulation of nucleocytoplasmic transport
GO:0051028 IEA mRNA transport
GO:0051607 IMP defense response to virus
GO:0051726 IMP regulation of cell cycle
GO:0060337 TAS type I interferon signaling pathway

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000004953 mxb myxovirus (influenza) resistance B protein_coding Danio_rerio
ENSDARG00000008019 mxg myxovirus (influenza virus) resistance G protein_coding Danio_rerio
ENSDARG00000021688 mxa myxovirus (influenza) resistance A protein_coding Danio_rerio
ENSDARG00000023369 mxd myxovirus (influenza virus) resistance D protein_coding Danio_rerio
ENSDARG00000026049 mxf myxovirus (influenza virus) resistance F protein_coding Danio_rerio
ENSDARG00000051795 si:dkeyp-110c12.3 si:dkeyp-110c12.3 protein_coding Danio_rerio
ENSDARG00000087845 mxb myxovirus (influenza) resistance B protein_coding Danio_rerio

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