C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: apoptosis-inducing factor, mitochondrion-associated, 3
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000183773 AIFM3 9606 + 22:20965108-20981360 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000399163 AIFM3-003 20965163-20981358 protein_coding
  ENST00000399167 AIFM3-002 20965108-20981360 protein_coding
  ENST00000405089 AIFM3-001 20967255-20981360 protein_coding
  ENST00000417515 AIFM3-007 20965167-20974814 nonsense_mediated_decay
  ENST00000426113 AIFM3-015 20967248-20974096 nonsense_mediated_decay
  ENST00000434714 AIFM3-014 20967159-20975778 protein_coding
  ENST00000440238 AIFM3-201 20967724-20981360 protein_coding
  ENST00000441376 AIFM3-009 20965172-20974096 protein_coding
  ENST00000465606 AIFM3-004 20974513-20981348 processed_transcript
  ENST00000467926 AIFM3-008 20965172-20973645 retained_intron
  ENST00000468124 AIFM3-016 20967249-20974297 processed_transcript
  ENST00000472575 AIFM3-011 20965177-20973619 retained_intron
  ENST00000479523 AIFM3-010 20965177-20967036 retained_intron
  ENST00000483107 AIFM3-005 20975692-20981356 processed_transcript
  ENST00000484206 AIFM3-017 20967255-20973678 retained_intron
  ENST00000486003 AIFM3-006 20976873-20981355 retained_intron
  ENST00000495869 AIFM3-012 20965268-20966798 retained_intron
  ENST00000496097 AIFM3-018 20967263-20974267 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; BrainColonOvaryENST00000399163ENST00000399167ENST00000440238ENST00000465606ENST00000483107
Transcript ID Brain Colon Ovary
ENST00000399163 9.042±0.00 4.974±0.00 N/A
ENST00000399167 8.249±0.00 N/A N/A
ENST00000440238 7.152±0.00 N/A N/A
ENST00000465606 13.807±0.00 N/A 18.260±0.00
ENST00000483107 4.310±0.00 N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0002X4 CIL_0002X4_0001 CGP 22:20917426-20981360
CIL_0002X3 CIL_0002X3_0001 CGP 22:20965108-20999038

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005739 IDA mitochondrion
GO:0005743 IDA mitochondrial inner membrane
GO:0005783 IDA endoplasmic reticulum
GO:0016491 IEA oxidoreductase activity
GO:0045454 IEA cell redox homeostasis
GO:0046872 IEA metal ion binding
GO:0050660 IEA flavin adenine dinucleotide binding
GO:0051537 IEA 2 iron, 2 sulfur cluster binding
GO:0055114 IEA oxidation-reduction process
GO:0097194 IDA execution phase of apoptosis

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000062780 AIFM3 apoptosis-inducing factor, mitochondrion-associated, 3 protein_coding Danio_rerio
ENSMUSG00000022763 Aifm3 apoptosis-inducing factor, mitochondrion-associated 3 protein_coding Mus_musculus

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