C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: apoptosis-inducing factor, mitochondrion-associated 3
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000022763 Aifm3 10090 + 16:17489611-17507485 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000023448 Aifm3-002 17489663-17507485 protein_coding
  ENSMUST00000115685 Aifm3-001 17489611-17507485 protein_coding
  ENSMUST00000124244 Aifm3-005 17502242-17503702 retained_intron
  ENSMUST00000132299 Aifm3-006 17502892-17505924 retained_intron
  ENSMUST00000134952 Aifm3-004 17499699-17507481 retained_intron
  ENSMUST00000149234 Aifm3-003 17489847-17505406 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000023448ENSMUST00000115685ENSMUST00000124244ENSMUST00000132299ENSMUST00000134952ENSMUST00000149234
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000023448 0.085±0.05 2.961±0.69 0.097±0.06 1.099±0.16 0.317±0.11 0.418±0.16 0.030±0.02 4.317±0.90 1.943±2.53 0.577±0.11 0.060±0.03 0.972±0.69 5.435±0.41 0.951±0.36
ENSMUST00000115685 N/A N/A 0.037±0.00 10.738±9.49 0.140±0.00 N/A N/A 1.552±0.00 N/A 0.372±0.00 N/A 0.367±0.00 1.518±1.23 N/A
ENSMUST00000124244 N/A N/A N/A N/A 0.099±0.00 N/A N/A N/A N/A N/A 0.073±0.02 N/A N/A N/A
ENSMUST00000132299 N/A N/A N/A 72.690±0.00 0.646±0.30 N/A N/A N/A 0.643±0.05 N/A 0.120±0.03 1.017±0.00 0.891±0.00 2.015±0.00
ENSMUST00000134952 N/A N/A N/A N/A 0.108±0.02 N/A N/A N/A N/A N/A 0.079±0.00 0.574±0.11 0.163±0.00 N/A
ENSMUST00000149234 N/A N/A N/A N/A 0.075±0.04 0.106±0.01 0.012±0.00 0.461±0.00 0.083±0.00 0.156±0.02 0.018±0.00 0.313±0.11 1.192±0.96 0.263±0.08

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0002X4 CIL_0002X4_0002 CGP 16:17451987-17507485
CIL_0002X3 CIL_0002X3_0002 CGP 16:17489611-17526333

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005739 ISS mitochondrion
GO:0005743 ISS mitochondrial inner membrane
GO:0005783 ISS endoplasmic reticulum
GO:0016491 IEA oxidoreductase activity
GO:0045454 IEA cell redox homeostasis
GO:0046872 IEA metal ion binding
GO:0050660 IEA flavin adenine dinucleotide binding
GO:0051537 IEA 2 iron, 2 sulfur cluster binding
GO:0055114 IEA oxidation-reduction process
GO:0097194 ISS execution phase of apoptosis

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000062780 AIFM3 apoptosis-inducing factor, mitochondrion-associated, 3 protein_coding Danio_rerio
ENSG00000183773 AIFM3 apoptosis-inducing factor, mitochondrion-associated, 3 protein_coding Homo_sapiens

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