C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: transmembrane protease, serine 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000184012 TMPRSS2 9606 - 21:41464551-41531116 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000332149 TMPRSS2-001 41464551-41508159 protein_coding
  ENST00000398585 TMPRSS2-201 41464553-41508065 protein_coding
  ENST00000424093 TMPRSS2-003 41473446-41508092 protein_coding
  ENST00000454499 TMPRSS2-008 41467734-41531116 protein_coding
  ENST00000455813 TMPRSS2-010 41494356-41506604 protein_coding
  ENST00000458356 TMPRSS2-009 41466009-41507982 protein_coding
  ENST00000463138 TMPRSS2-004 41488489-41508114 processed_transcript
  ENST00000469395 TMPRSS2-005 41467766-41468837 retained_intron
  ENST00000488556 TMPRSS2-006 41465890-41468102 retained_intron
  ENST00000489201 TMPRSS2-011 41529789-41531098 retained_intron
  ENST00000497881 TMPRSS2-002 41486467-41508158 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000332149ENST00000398585ENST00000424093ENST00000454499ENST00000458356ENST00000469395ENST00000497881
Transcript ID Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000332149 N/A 1.693±0.00 N/A 2.137±0.30 3.076±2.00 N/A 24.589±0.00 3.517±2.39 9.919±6.97 0.032±0.00 10.975±12.85 0.055±0.00 0.441±0.00
ENST00000398585 N/A N/A N/A N/A N/A N/A 0.321±0.00 1.426±0.00 N/A N/A 1.236±0.00 N/A N/A
ENST00000424093 N/A N/A N/A N/A N/A N/A 0.927±0.00 N/A N/A N/A N/A N/A N/A
ENST00000454499 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 1.521±0.00
ENST00000458356 N/A 3.331±0.00 N/A 3.812±0.00 8.911±0.00 N/A N/A 0.473±0.00 N/A N/A 90.160±0.00 0.081±0.00 0.880±0.00
ENST00000469395 0.176±0.00 N/A 0.152±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000497881 0.227±0.00 N/A 0.060±0.03 N/A N/A 0.020±0.00 N/A N/A N/A N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00036K CIL_00036K_0001 CGP 21:41464551-41767106

Gene Ontology
GO IDEvidence TypeGO Description
GO:0003824 IEA catalytic activity
GO:0004252 IEA serine-type endopeptidase activity
GO:0005044 IEA scavenger receptor activity
GO:0005515 IPI:IEA protein binding
GO:0005886 IDA plasma membrane
GO:0005887 TAS integral component of plasma membrane
GO:0006508 IDA:IEA proteolysis
GO:0006898 IEA receptor-mediated endocytosis
GO:0008236 TAS serine-type peptidase activity
GO:0016020 IEA membrane
GO:0016540 IMP protein autoprocessing
GO:0046598 IDA positive regulation of viral entry into host cell
GO:0070062 IDA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000045889 tmprss2 transmembrane protease, serine 2 protein_coding Danio_rerio
ENSMUSG00000000385 Tmprss2 transmembrane protease, serine 2 protein_coding Mus_musculus

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