C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: adrenoceptor alpha 2C
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000184160 ADRA2C 9606 + 4:3766348-3768526 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000330055 ADRA2C-002 3766398-3768526 protein_coding
  ENST00000509482 ADRA2C-001 3766348-3768491 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000330055ENST00000509482
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000330055 12.437±0.00 11.466±0.00 0.644±0.00 1.207±0.57 3.513±3.28 3.538±3.45 2.356±1.97 21.512±0.00 0.345±0.00 2.936±0.00 0.629±0.00 4.948±4.23 19.661±7.12 9.572±8.61
ENST00000509482 N/A N/A N/A 0.408±0.03 N/A N/A N/A N/A 0.359±0.00 0.488±0.00 1.075±0.00 1.428±1.26 N/A 2.785±2.26

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004930 IEA G-protein coupled receptor activity
GO:0004938 IDA alpha2-adrenergic receptor activity
GO:0005515 IPI protein binding
GO:0005737 IDA cytoplasm
GO:0005768 TAS endosome
GO:0005886 TAS plasma membrane
GO:0005887 IDA integral component of plasma membrane
GO:0006112 TAS energy reserve metabolic process
GO:0006940 IEA regulation of smooth muscle contraction
GO:0007186 TAS:IEA G-protein coupled receptor signaling pathway
GO:0007267 TAS cell-cell signaling
GO:0007565 IEA female pregnancy
GO:0007596 TAS blood coagulation
GO:0010700 NAS negative regulation of norepinephrine secretion
GO:0016021 IEA integral component of membrane
GO:0019229 IEA regulation of vasoconstriction
GO:0030168 TAS platelet activation
GO:0030424 IEA axon
GO:0031694 IPI alpha-2A adrenergic receptor binding
GO:0032148 IDA activation of protein kinase B activity
GO:0032811 NAS negative regulation of epinephrine secretion
GO:0035625 IDA epidermal growth factor-activated receptor transactivation by G-protein coupled receptor signaling pathway
GO:0042803 IDA protein homodimerization activity
GO:0043679 IEA axon terminus
GO:0044281 TAS small molecule metabolic process
GO:0045666 IDA positive regulation of neuron differentiation
GO:0045907 IEA positive regulation of vasoconstriction
GO:0046982 IPI protein heterodimerization activity
GO:0050796 TAS regulation of insulin secretion
GO:0051379 IDA epinephrine binding
GO:0051930 IEA regulation of sensory perception of pain
GO:0070473 IEA negative regulation of uterine smooth muscle contraction
GO:0071875 IEA adrenergic receptor signaling pathway
GO:0071883 IDA activation of MAPK activity by adrenergic receptor signaling pathway

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000069669 adra2c adrenergic, alpha-2C-, receptor protein_coding Danio_rerio
ENSMUSG00000045318 Adra2c adrenergic receptor, alpha 2c protein_coding Mus_musculus

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