C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: adrenoceptor alpha 2C
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000330055 ADRA2C-002 ENSG00000184160 9606 + 4:3766398-3768526 protein_coding

Homo sapiens EnsemblGRCh38

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Structures from Ensembl
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Transcripts
Structures from Ensembl
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Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000330055
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000330055 12.437±0.00 11.466±0.00 0.644±0.00 1.207±0.57 3.513±3.28 3.538±3.45 2.356±1.97 21.512±0.00 0.345±0.00 2.936±0.00 0.629±0.00 4.948±4.23 19.661±7.12 9.572±8.61

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0004930 IEA G-protein coupled receptor activity
GO:0004938 IDA alpha2-adrenergic receptor activity
GO:0005515 IPI protein binding
GO:0005737 IDA cytoplasm
GO:0005768 TAS endosome
GO:0005886 TAS plasma membrane
GO:0005887 IDA integral component of plasma membrane
GO:0006112 TAS energy reserve metabolic process
GO:0007186 TAS:IEA G-protein coupled receptor signaling pathway
GO:0007267 TAS cell-cell signaling
GO:0007565 IEA female pregnancy
GO:0007596 TAS blood coagulation
GO:0010700 NAS negative regulation of norepinephrine secretion
GO:0016021 IEA integral component of membrane
GO:0030168 TAS platelet activation
GO:0030424 IEA axon
GO:0031694 IPI alpha-2A adrenergic receptor binding
GO:0032148 IDA activation of protein kinase B activity
GO:0032811 NAS negative regulation of epinephrine secretion
GO:0035625 IDA epidermal growth factor-activated receptor transactivation by G-protein coupled receptor signaling pathway
GO:0042803 IDA protein homodimerization activity
GO:0043679 IEA axon terminus
GO:0044281 TAS small molecule metabolic process
GO:0045666 IDA positive regulation of neuron differentiation
GO:0045907 IEA positive regulation of vasoconstriction
GO:0046982 IPI protein heterodimerization activity
GO:0050796 TAS regulation of insulin secretion
GO:0051379 IDA epinephrine binding
GO:0051930 IEA regulation of sensory perception of pain
GO:0070473 IEA negative regulation of uterine smooth muscle contraction
GO:0071883 IDA activation of MAPK activity by adrenergic receptor signaling pathway

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000049545 Adra2c-201 protein_coding Mus_musculus 0 1838
ENSDART00000123912 adra2da-201 protein_coding Danio_rerio 0 209
ENSDART00000018663 adra2b-201 protein_coding Danio_rerio 1e-34 152
ENSDART00000060089 FP236542.1-201 protein_coding Danio_rerio 1e-20 106

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