C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: forkhead box O4
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000184481 FOXO4 9606 + X:71096197-71103535 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000341558 FOXO4-002 71096529-71102084 protein_coding
  ENST00000374259 FOXO4-001 71096197-71103535 protein_coding
  ENST00000464598 FOXO4-003 71099308-71100843 processed_transcript
  ENST00000466874 FOXO4-005 71096253-71100772 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000374259ENST00000466874
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000374259 10.870±0.00 3.789±0.00 0.746±0.00 2.587±1.62 5.349±3.15 8.872±0.00 5.002±3.03 2.099±1.27 2.307±0.07 7.703±0.00 13.446±8.09 8.306±5.77 124.503±29.95 8.122±0.57
ENST00000466874 N/A N/A 1.256±0.00 N/A N/A N/A N/A N/A N/A N/A N/A 7.602±0.00 127.721±0.00 12.440±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00009X CIL_00009X_0001 CGP X:71056332-71103535
CIL_0000A0 CIL_0000A0_0001 CGP X:71096197-71106788

Gene Ontology
GO IDEvidence TypeGO Description
GO:0003677 IDA DNA binding
GO:0003700 IDA:IEA sequence-specific DNA binding transcription factor activity
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005654 TAS nucleoplasm
GO:0005737 IDA cytoplasm
GO:0005829 IDA cytosol
GO:0006355 IDA:IEA regulation of transcription, DNA-templated
GO:0006366 TAS transcription from RNA polymerase II promoter
GO:0007050 IDA cell cycle arrest
GO:0007095 IEA mitotic G2 DNA damage checkpoint
GO:0007173 TAS epidermal growth factor receptor signaling pathway
GO:0007517 IEA muscle organ development
GO:0008134 IPI transcription factor binding
GO:0008285 IDA negative regulation of cell proliferation
GO:0008286 IDA insulin receptor signaling pathway
GO:0008543 TAS fibroblast growth factor receptor signaling pathway
GO:0016525 IDA negative regulation of angiogenesis
GO:0019899 IPI enzyme binding
GO:0038095 TAS Fc-epsilon receptor signaling pathway
GO:0043565 IMP:IEA sequence-specific DNA binding
GO:0045087 TAS innate immune response
GO:0045893 IEA positive regulation of transcription, DNA-templated
GO:0048011 TAS neurotrophin TRK receptor signaling pathway
GO:0048015 TAS phosphatidylinositol-mediated signaling
GO:0048863 IMP stem cell differentiation
GO:0051151 IDA negative regulation of smooth muscle cell differentiation
GO:0070317 IDA negative regulation of G0 to G1 transition

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000055792 FOXO4 forkhead box O4 protein_coding Danio_rerio
ENSMUSG00000042903 Foxo4 forkhead box O4 protein_coding Mus_musculus

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