C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: forkhead box O4
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000042903 Foxo4 10090 + X:101254528-101260873 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000062000 Foxo4-001 101254528-101260873 protein_coding
  ENSMUST00000138437 Foxo4-002 101254821-101259233 protein_coding
  ENSMUST00000150558 Foxo4-003 101254567-101256435 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000062000ENSMUST00000138437
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000062000 8.465±0.82 6.486±2.55 5.409±0.77 3.442±1.09 8.271±2.66 7.963±0.72 7.320±1.19 6.982±0.74 5.891±1.57 11.446±0.71 45.078±7.18 6.449±1.75 222.601±65.84 2.126±0.66
ENSMUST00000138437 9.795±1.39 9.518±1.27 N/A 1.328±0.00 9.669±4.71 9.902±3.30 6.725±1.26 7.628±1.71 4.974±0.74 9.539±1.15 N/A 10.601±3.47 N/A 1.012±0.04

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00009X CIL_00009X_0002 CGP X:101097786-101260873
CIL_0000A0 CIL_0000A0_0002 CGP X:101254528-101263992

Gene Ontology
GO IDEvidence TypeGO Description
GO:0003677 ISS DNA binding
GO:0003700 ISS sequence-specific DNA binding transcription factor activity
GO:0005515 IPI protein binding
GO:0005634 ISS nucleus
GO:0005737 IEA cytoplasm
GO:0005829 ISS cytosol
GO:0006351 IEA transcription, DNA-templated
GO:0006355 ISS regulation of transcription, DNA-templated
GO:0007050 ISS cell cycle arrest
GO:0007095 IDA mitotic G2 DNA damage checkpoint
GO:0007517 IEA muscle organ development
GO:0008134 ISS transcription factor binding
GO:0008285 ISS negative regulation of cell proliferation
GO:0008286 ISS insulin receptor signaling pathway
GO:0016525 ISS negative regulation of angiogenesis
GO:0019899 ISS enzyme binding
GO:0043565 IDA sequence-specific DNA binding
GO:0045893 IDA positive regulation of transcription, DNA-templated
GO:0048863 ISS stem cell differentiation
GO:0051151 ISS negative regulation of smooth muscle cell differentiation
GO:0070317 ISS negative regulation of G0 to G1 transition

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000055792 FOXO4 forkhead box O4 protein_coding Danio_rerio
ENSG00000184481 FOXO4 forkhead box O4 protein_coding Homo_sapiens

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