C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: inositol polyphosphate-5-phosphatase J
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000185133 INPP5J 9606 + 22:31122731-31134696 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000331075 INPP5J-002 31122966-31134696 protein_coding
  ENST00000400294 INPP5J-001 31122994-31134696 protein_coding
  ENST00000401755 INPP5J-008 31127802-31134636 protein_coding
  ENST00000402238 INPP5J-006 31127760-31134636 protein_coding
  ENST00000404390 INPP5J-004 31122994-31134696 protein_coding
  ENST00000404453 INPP5J-007 31127789-31134636 protein_coding
  ENST00000405300 INPP5J-003 31122994-31134696 protein_coding
  ENST00000412277 INPP5J-201 31122923-31134696 protein_coding
  ENST00000412985 INPP5J-010 31122966-31125373 protein_coding
  ENST00000420017 INPP5J-011 31122984-31127037 protein_coding
  ENST00000461241 INPP5J-005 31122975-31134696 retained_intron
  ENST00000463528 INPP5J-009 31122731-31124881 processed_transcript
  ENST00000620191 INPP5J-202 31122923-31134696 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000331075ENST00000400294ENST00000402238ENST00000404390ENST00000404453ENST00000405300ENST00000412277ENST00000412985ENST00000420017ENST00000461241ENST00000620191
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000331075 N/A 0.162±0.00 N/A 1.940±1.09 0.522±0.00 N/A 2.671±2.40 3.727±0.00 N/A 0.158±0.00 0.203±0.00 0.930±0.70 0.088±0.02 0.346±0.08
ENST00000400294 N/A 0.041±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.334±0.00 N/A N/A
ENST00000402238 N/A N/A N/A N/A 0.484±0.00 N/A N/A N/A 0.031±0.00 0.088±0.00 0.235±0.00 N/A 0.124±0.00 N/A
ENST00000404390 0.026±0.00 N/A N/A 3.709±0.00 N/A 0.248±0.00 0.537±0.00 6.308±0.00 N/A 0.128±0.00 N/A 2.096±0.00 N/A 0.315±0.00
ENST00000404453 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 3.044±0.00 0.188±0.00 N/A
ENST00000405300 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.328±0.00
ENST00000412277 N/A N/A N/A N/A N/A 0.416±0.00 0.986±0.00 3.423±0.00 N/A N/A N/A N/A N/A N/A
ENST00000412985 0.163±0.00 N/A N/A N/A 0.547±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000420017 0.386±0.00 0.138±0.00 N/A N/A N/A N/A N/A N/A N/A N/A 0.617±0.00 N/A N/A N/A
ENST00000461241 N/A N/A 0.286±0.00 N/A N/A 0.108±0.00 N/A N/A N/A N/A N/A N/A 0.057±0.00 N/A
ENST00000620191 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.501±0.00 N/A N/A N/A

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001726 IDA ruffle
GO:0004445 IEA inositol-polyphosphate 5-phosphatase activity
GO:0005737 IDA cytoplasm
GO:0005829 TAS cytosol
GO:0005886 IEA plasma membrane
GO:0006644 TAS phospholipid metabolic process
GO:0006661 TAS phosphatidylinositol biosynthetic process
GO:0010977 IEA negative regulation of neuron projection development
GO:0017124 IEA SH3 domain binding
GO:0030426 IEA growth cone
GO:0031115 IEA negative regulation of microtubule polymerization
GO:0033137 IEA negative regulation of peptidyl-serine phosphorylation
GO:0034485 IEA phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity
GO:0043198 IEA dendritic shaft
GO:0043647 TAS inositol phosphate metabolic process
GO:0044281 TAS small molecule metabolic process
GO:0046856 IEA phosphatidylinositol dephosphorylation
GO:0052658 IEA inositol-1,4,5-trisphosphate 5-phosphatase activity
GO:0052659 IEA inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000078542 inpp5ja inositol polyphosphate-5-phosphatase Ja protein_coding Danio_rerio
ENSDARG00000093359 inpp5jb inositol polyphosphate-5-phosphatase Jb protein_coding Danio_rerio
ENSMUSG00000034570 Inpp5j inositol polyphosphate 5-phosphatase J protein_coding Mus_musculus

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