C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: inositol polyphosphate 5-phosphatase J
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000034570 Inpp5j 10090 - 11:3494375-3504821 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000044507 Inpp5j-001 3494375-3504821 protein_coding
  ENSMUST00000110018 Inpp5j-003 3494382-3504771 nonsense_mediated_decay
  ENSMUST00000110019 Inpp5j-002 3494547-3504786 nonsense_mediated_decay
  ENSMUST00000148939 Inpp5j-005 3494382-3502134 protein_coding
  ENSMUST00000154756 Inpp5j-004 3494382-3504774 non_stop_decay
  ENSMUST00000183684 Inpp5j-006 3498950-3504799 nonsense_mediated_decay

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000044507ENSMUST00000110018ENSMUST00000110019ENSMUST00000148939ENSMUST00000154756ENSMUST00000183684
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000044507 0.603±0.40 0.321±0.06 0.318±0.17 2.688±2.42 0.977±0.20 35.657±1.67 5.781±1.93 5.734±1.26 0.149±0.14 0.814±0.29 0.730±0.12 1.806±1.11 0.035±0.01 0.072±0.00
ENSMUST00000110018 N/A N/A N/A 4.635±0.00 0.191±0.00 N/A N/A 2.069±0.16 N/A N/A N/A 1.771±0.00 N/A N/A
ENSMUST00000110019 0.654±0.51 0.426±0.01 0.233±0.01 1.974±1.69 0.754±0.34 N/A 2.006±0.07 3.690±1.30 0.199±0.12 0.764±0.00 0.258±0.04 1.246±0.29 N/A N/A
ENSMUST00000148939 0.697±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.326±0.00 N/A 0.102±0.00 1.474±0.81
ENSMUST00000154756 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.098±0.00 N/A
ENSMUST00000183684 N/A 0.269±0.00 N/A 0.241±0.05 N/A N/A N/A N/A 0.014±0.00 N/A 0.187±0.01 1.436±0.00 0.083±0.00 N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_000508 CIL_000508_0002 CGP 11:3494375-3517351

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001726 ISO ruffle
GO:0004445 IEA inositol-polyphosphate 5-phosphatase activity
GO:0005737 ISO cytoplasm
GO:0005886 IDA plasma membrane
GO:0010977 IDA negative regulation of neuron projection development
GO:0016311 IDA dephosphorylation
GO:0017124 IEA SH3 domain binding
GO:0030426 IDA growth cone
GO:0031115 IEA negative regulation of microtubule polymerization
GO:0033137 IDA negative regulation of peptidyl-serine phosphorylation
GO:0034485 IDA phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity
GO:0043198 IDA dendritic shaft
GO:0046856 IEA phosphatidylinositol dephosphorylation
GO:0052658 IEA inositol-1,4,5-trisphosphate 5-phosphatase activity
GO:0052659 IEA inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000078542 inpp5ja inositol polyphosphate-5-phosphatase Ja protein_coding Danio_rerio
ENSDARG00000093359 inpp5jb inositol polyphosphate-5-phosphatase Jb protein_coding Danio_rerio
ENSG00000185133 INPP5J inositol polyphosphate-5-phosphatase J protein_coding Homo_sapiens

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