C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: neuropeptide Y receptor Y2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000185149 NPY2R 9606 + 4:155208629-155217078 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000329476 NPY2R-001 155208629-155217076 protein_coding
  ENST00000506608 NPY2R-002 155208735-155217078 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastColonHeartLiverLungOvaryTestisENST00000329476ENST00000506608
Transcript ID Adipose Adrenal Brain Breast Colon Heart Liver Lung Ovary Testis
ENST00000329476 N/A N/A 0.313±0.03 0.204±0.00 N/A N/A 0.004±0.00 N/A 0.001±0.00 0.735±0.00
ENST00000506608 0.006±0.00 0.003±0.00 0.126±0.00 0.203±0.00 0.297±0.22 0.016±0.00 0.019±0.01 0.132±0.00 0.004±0.00 0.454±0.27

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0000O0 CIL_0000O0_0002 CGP 4:154781213-155217078
CIL_0000O6 CIL_0000O6_0002 CGP 4:155208629-155376970

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001601 IEA peptide YY receptor activity
GO:0001662 IEA behavioral fear response
GO:0002793 IEA positive regulation of peptide secretion
GO:0003151 IMP outflow tract morphogenesis
GO:0003214 IMP cardiac left ventricle morphogenesis
GO:0004872 TAS receptor activity
GO:0004930 IEA G-protein coupled receptor activity
GO:0004983 TAS neuropeptide Y receptor activity
GO:0005246 TAS calcium channel regulator activity
GO:0005515 IPI protein binding
GO:0005886 TAS plasma membrane
GO:0005887 IEA integral component of plasma membrane
GO:0007186 IEA G-protein coupled receptor signaling pathway
GO:0007193 TAS adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway
GO:0007204 IEA positive regulation of cytosolic calcium ion concentration
GO:0007218 IEA neuropeptide signaling pathway
GO:0007263 IEA nitric oxide mediated signal transduction
GO:0007626 TAS locomotory behavior
GO:0016020 IEA membrane
GO:0016021 IEA integral component of membrane
GO:0030818 IEA negative regulation of cAMP biosynthetic process
GO:0031513 IEA nonmotile primary cilium
GO:0031645 IEA negative regulation of neurological system process
GO:0033603 IEA positive regulation of dopamine secretion
GO:0045785 IEA positive regulation of cell adhesion
GO:0045987 IEA positive regulation of smooth muscle contraction
GO:0046010 IEA positive regulation of circadian sleep/wake cycle, non-REM sleep
GO:0046903 IEA secretion
GO:0050805 IEA negative regulation of synaptic transmission
GO:0051048 IEA negative regulation of secretion
GO:0051930 IEA regulation of sensory perception of pain
GO:0051967 IEA negative regulation of synaptic transmission, glutamatergic
GO:0090394 IEA negative regulation of excitatory postsynaptic membrane potential
GO:2000252 IEA negative regulation of feeding behavior

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000057718 npy2rl neuropeptide Y receptor Y2, like protein_coding Danio_rerio
ENSDARG00000089943 npy2rl neuropeptide Y receptor Y2, like protein_coding Danio_rerio
ENSDARG00000094763 npy2r neuropeptide Y receptor Y2 protein_coding Danio_rerio
ENSMUSG00000028004 Npy2r neuropeptide Y receptor Y2 protein_coding Mus_musculus

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