C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: neuropeptide Y receptor Y2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000028004 Npy2r 10090 - 3:82538383-82548084 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000029633 Npy2r-004 82538383-82548084 protein_coding
  ENSMUST00000098997 Npy2r-001 82538386-82548052 protein_coding
  ENSMUST00000182181 Npy2r-002 82539949-82547960 protein_coding
  ENSMUST00000182831 Npy2r-003 82539949-82547960 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungOvaryPlacentaTestisENSMUST00000029633ENSMUST00000098997ENSMUST00000182181ENSMUST00000182831
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Ovary Placenta Testis
ENSMUST00000029633 N/A N/A N/A 0.233±0.19 N/A N/A N/A 0.030±0.00 N/A N/A 0.022±0.00 0.001±0.00 N/A
ENSMUST00000098997 0.025±0.00 N/A 0.066±0.00 0.125±0.07 0.038±0.00 0.293±0.16 0.015±0.01 0.048±0.01 0.006±0.00 N/A 0.125±0.07 0.007±0.00 0.055±0.02
ENSMUST00000182181 0.220±0.05 N/A N/A 4.344±0.00 0.101±0.02 N/A 0.024±0.00 0.040±0.02 0.007±0.00 N/A 0.128±0.03 N/A 0.169±0.00
ENSMUST00000182831 0.366±0.27 0.993±0.12 0.034±0.00 0.800±0.89 0.202±0.15 0.521±0.14 N/A 0.053±0.02 N/A 0.022±0.00 0.125±0.06 0.021±0.00 0.069±0.00

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001601 IDA peptide YY receptor activity
GO:0001662 IEA behavioral fear response
GO:0002793 IEA positive regulation of peptide secretion
GO:0003151 IEA outflow tract morphogenesis
GO:0003214 IEA cardiac left ventricle morphogenesis
GO:0004983 IDA neuropeptide Y receptor activity
GO:0005515 IEA protein binding
GO:0005886 IEA plasma membrane
GO:0005887 IEA integral component of plasma membrane
GO:0007186 IMP G-protein coupled receptor signaling pathway
GO:0007193 IDA adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway
GO:0007204 IEA positive regulation of cytosolic calcium ion concentration
GO:0007218 IEA neuropeptide signaling pathway
GO:0007263 IEA nitric oxide mediated signal transduction
GO:0016020 IEA membrane
GO:0016021 IEA integral component of membrane
GO:0030818 IEA negative regulation of cAMP biosynthetic process
GO:0031513 IDA nonmotile primary cilium
GO:0031645 IEA negative regulation of neurological system process
GO:0033603 IEA positive regulation of dopamine secretion
GO:0045785 IEA positive regulation of cell adhesion
GO:0045987 IEA positive regulation of smooth muscle contraction
GO:0046010 IEA positive regulation of circadian sleep/wake cycle, non-REM sleep
GO:0046903 IEA secretion
GO:0050805 IEA negative regulation of synaptic transmission
GO:0051048 IEA negative regulation of secretion
GO:0051930 IEA regulation of sensory perception of pain
GO:0051967 IEA negative regulation of synaptic transmission, glutamatergic
GO:0090394 IEA negative regulation of excitatory postsynaptic membrane potential
GO:2000252 IEA negative regulation of feeding behavior

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000057718 npy2rl neuropeptide Y receptor Y2, like protein_coding Danio_rerio
ENSDARG00000089943 npy2rl neuropeptide Y receptor Y2, like protein_coding Danio_rerio
ENSDARG00000094763 npy2r neuropeptide Y receptor Y2 protein_coding Danio_rerio
ENSG00000185149 NPY2R neuropeptide Y receptor Y2 protein_coding Homo_sapiens

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