C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: cyclin-dependent kinase 10
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000185324 CDK10 9606 + 16:89680737-89696364 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000331006 CDK10-016 89680737-89696353 protein_coding
  ENST00000353379 CDK10-001 89686668-89696364 protein_coding
  ENST00000378277 CDK10-015 89686713-89692682 retained_intron
  ENST00000472018 CDK10-002 89686700-89696354 retained_intron
  ENST00000502547 CDK10-009 89686684-89691507 nonsense_mediated_decay
  ENST00000503560 CDK10-013 89686951-89690557 processed_transcript
  ENST00000504473 CDK10-014 89686972-89693495 retained_intron
  ENST00000505473 CDK10-003 89686670-89696164 protein_coding
  ENST00000505733 CDK10-006 89686690-89696354 retained_intron
  ENST00000507205 CDK10-005 89686692-89694040 retained_intron
  ENST00000508723 CDK10-008 89686670-89691535 nonsense_mediated_decay
  ENST00000510811 CDK10-019 89686691-89696038 nonsense_mediated_decay
  ENST00000511415 CDK10-012 89686680-89693402 nonsense_mediated_decay
  ENST00000512912 CDK10-011 89686690-89692514 nonsense_mediated_decay
  ENST00000514965 CDK10-010 89686728-89691512 processed_transcript
  ENST00000561477 CDK10-021 89691826-89694454 retained_intron
  ENST00000564192 CDK10-022 89686706-89694972 protein_coding
  ENST00000565470 CDK10-017 89694184-89696094 nonsense_mediated_decay
  ENST00000567932 CDK10-020 89692237-89693718 retained_intron
  ENST00000568456 CDK10-004 89689503-89691845 retained_intron
  ENST00000617879 CDK10-201 89690606-89695775 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000331006ENST00000353379ENST00000472018ENST00000505473ENST00000507205ENST00000510811ENST00000512912ENST00000514965ENST00000564192ENST00000568456ENST00000617879
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000331006 N/A N/A N/A N/A 0.412±0.00 N/A 0.243±0.06 N/A N/A N/A 0.394±0.00 N/A N/A N/A
ENST00000353379 4.607±0.00 N/A N/A 2.637±1.19 6.350±0.00 6.822±0.00 1.794±0.00 10.812±0.00 17.571±0.00 5.733±0.00 1.120±0.00 9.759±0.00 11.375±3.91 5.455±0.00
ENST00000472018 N/A 5.984±0.00 1.045±0.00 1.711±0.00 2.474±1.02 N/A 1.424±0.00 4.176±0.00 3.051±0.00 3.800±2.81 N/A 8.910±4.23 6.771±0.00 16.580±14.08
ENST00000505473 N/A N/A 1.960±0.00 N/A N/A N/A N/A N/A 6.056±0.00 N/A N/A N/A N/A N/A
ENST00000507205 N/A N/A N/A N/A N/A N/A N/A N/A 0.776±0.00 N/A N/A N/A N/A N/A
ENST00000510811 N/A N/A N/A 3.887±0.00 N/A N/A N/A N/A 0.782±0.00 N/A 1.638±0.00 5.754±0.00 N/A N/A
ENST00000512912 N/A N/A N/A N/A N/A N/A N/A N/A N/A 1.995±0.00 N/A N/A N/A N/A
ENST00000514965 N/A N/A N/A N/A N/A N/A N/A 4.650±0.00 2.496±0.00 N/A N/A N/A N/A N/A
ENST00000564192 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 15.012±0.00 N/A
ENST00000568456 N/A N/A N/A N/A 0.846±0.00 2.150±0.00 N/A N/A 0.608±0.00 N/A N/A N/A N/A N/A
ENST00000617879 N/A N/A N/A N/A N/A N/A N/A 2.309±0.00 N/A N/A N/A 1.923±0.00 N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00032T CIL_00032T_0001 CGP 16:89657802-89696364
CIL_00032S CIL_00032S_0001 CGP 16:89680737-89701705

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004672 IEA protein kinase activity
GO:0004674 IEA protein serine/threonine kinase activity
GO:0004693 IEA cyclin-dependent protein serine/threonine kinase activity
GO:0004713 IEA protein tyrosine kinase activity
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0006468 IEA protein phosphorylation
GO:0007089 TAS traversing start control point of mitotic cell cycle
GO:0008285 TAS negative regulation of cell proliferation
GO:0016301 IEA kinase activity
GO:0016310 IEA phosphorylation
GO:0016772 IEA transferase activity, transferring phosphorus-containing groups
GO:0043410 IEA positive regulation of MAPK cascade
GO:0097472 IEA cyclin-dependent protein kinase activity

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000034256 cdk10 cyclin-dependent kinase 10 protein_coding Danio_rerio
ENSMUSG00000033862 Cdk10 cyclin-dependent kinase 10 protein_coding Mus_musculus

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