C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: mitogen-activated protein kinase 11
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000185386 MAPK11 9606 - 22:50263713-50270767 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000330651 MAPK11-001 50263713-50270393 protein_coding
  ENST00000395764 MAPK11-003 50263715-50270393 nonsense_mediated_decay
  ENST00000417877 MAPK11-002 50263739-50270393 nonsense_mediated_decay
  ENST00000495277 MAPK11-004 50267138-50270767 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000330651ENST00000395764ENST00000417877ENST00000495277
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000330651 6.908±0.00 10.662±0.00 N/A 8.248±0.00 7.562±0.00 0.997±0.97 1.931±0.00 5.641±0.00 0.349±0.00 6.904±0.00 0.722±0.00 3.257±1.83 4.329±2.28 1.659±0.59
ENST00000395764 4.066±0.00 N/A 0.047±0.00 0.982±0.00 3.390±0.00 0.596±0.54 N/A N/A N/A N/A N/A 2.382±1.98 2.327±0.00 2.856±0.00
ENST00000417877 N/A N/A N/A N/A 0.073±0.00 0.031±0.00 0.041±0.00 N/A 0.097±0.00 0.095±0.00 N/A N/A N/A N/A
ENST00000495277 N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.928±0.00 N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00009B CIL_00009B_0001 CGP 22:50245450-50270767
CIL_00009A CIL_00009A_0001 CGP 22:50263713-50307627

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000187 TAS activation of MAPK activity
GO:0002224 TAS toll-like receptor signaling pathway
GO:0002755 TAS MyD88-dependent toll-like receptor signaling pathway
GO:0002756 TAS MyD88-independent toll-like receptor signaling pathway
GO:0004672 IEA protein kinase activity
GO:0004674 TAS protein serine/threonine kinase activity
GO:0004707 IDA MAP kinase activity
GO:0004713 IEA protein tyrosine kinase activity
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0005654 TAS nucleoplasm
GO:0005829 TAS cytosol
GO:0006351 IEA transcription, DNA-templated
GO:0006468 IEA protein phosphorylation
GO:0006950 IDA response to stress
GO:0007165 TAS signal transduction
GO:0007265 TAS Ras protein signal transduction
GO:0009103 IEA lipopolysaccharide biosynthetic process
GO:0010467 TAS gene expression
GO:0016020 IEA membrane
GO:0016070 TAS RNA metabolic process
GO:0016071 TAS mRNA metabolic process
GO:0016772 IEA transferase activity, transferring phosphorus-containing groups
GO:0016773 IEA phosphotransferase activity, alcohol group as acceptor
GO:0034134 TAS toll-like receptor 2 signaling pathway
GO:0034138 TAS toll-like receptor 3 signaling pathway
GO:0034142 TAS toll-like receptor 4 signaling pathway
GO:0034146 TAS toll-like receptor 5 signaling pathway
GO:0034162 TAS toll-like receptor 9 signaling pathway
GO:0034166 TAS toll-like receptor 10 signaling pathway
GO:0035556 IDA intracellular signal transduction
GO:0035666 TAS TRIF-dependent toll-like receptor signaling pathway
GO:0038123 TAS toll-like receptor TLR1:TLR2 signaling pathway
GO:0038124 TAS toll-like receptor TLR6:TLR2 signaling pathway
GO:0042692 TAS muscle cell differentiation
GO:0045087 TAS innate immune response
GO:0048011 TAS neurotrophin TRK receptor signaling pathway
GO:0051090 TAS regulation of sequence-specific DNA binding transcription factor activity
GO:0051149 TAS positive regulation of muscle cell differentiation
GO:0051403 TAS stress-activated MAPK cascade

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000045836 mapk11 mitogen-activated protein kinase 11 protein_coding Danio_rerio
ENSMUSG00000053137 Mapk11 mitogen-activated protein kinase 11 protein_coding Mus_musculus

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