C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: mitogen-activated protein kinase 11
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000330651 MAPK11-001 ENSG00000185386 9606 - 22:50263713-50270393 protein_coding

Homo sapiens EnsemblGRCh38

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Genes
Structures from Ensembl
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Transcripts
Structures from Ensembl
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Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000330651
Transcript ID Adipose Adrenal Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000330651 6.908±0.00 10.662±0.00 8.248±0.00 7.562±0.00 0.997±0.97 1.931±0.00 5.641±0.00 0.349±0.00 6.904±0.00 0.722±0.00 3.257±1.83 4.329±2.28 1.659±0.59

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00009B CIL_00009B_0001 CGP 22:50245450-50270767
CIL_00009A CIL_00009A_0001 CGP 22:50263713-50307627

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000187 TAS activation of MAPK activity
GO:0002224 TAS toll-like receptor signaling pathway
GO:0002755 TAS MyD88-dependent toll-like receptor signaling pathway
GO:0002756 TAS MyD88-independent toll-like receptor signaling pathway
GO:0004672 IEA protein kinase activity
GO:0004674 TAS protein serine/threonine kinase activity
GO:0004707 IDA MAP kinase activity
GO:0004713 IEA protein tyrosine kinase activity
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0005654 TAS nucleoplasm
GO:0005829 TAS cytosol
GO:0006351 IEA transcription, DNA-templated
GO:0006468 IEA protein phosphorylation
GO:0006950 IDA response to stress
GO:0007165 TAS signal transduction
GO:0007265 TAS Ras protein signal transduction
GO:0009103 IEA lipopolysaccharide biosynthetic process
GO:0010467 TAS gene expression
GO:0016020 IEA membrane
GO:0016070 TAS RNA metabolic process
GO:0016071 TAS mRNA metabolic process
GO:0016772 IEA transferase activity, transferring phosphorus-containing groups
GO:0016773 IEA phosphotransferase activity, alcohol group as acceptor
GO:0034134 TAS toll-like receptor 2 signaling pathway
GO:0034138 TAS toll-like receptor 3 signaling pathway
GO:0034142 TAS toll-like receptor 4 signaling pathway
GO:0034146 TAS toll-like receptor 5 signaling pathway
GO:0034162 TAS toll-like receptor 9 signaling pathway
GO:0034166 TAS toll-like receptor 10 signaling pathway
GO:0035556 IDA intracellular signal transduction
GO:0035666 TAS TRIF-dependent toll-like receptor signaling pathway
GO:0038123 TAS toll-like receptor TLR1:TLR2 signaling pathway
GO:0038124 TAS toll-like receptor TLR6:TLR2 signaling pathway
GO:0042692 TAS muscle cell differentiation
GO:0045087 TAS innate immune response
GO:0048011 TAS neurotrophin TRK receptor signaling pathway
GO:0051090 TAS regulation of sequence-specific DNA binding transcription factor activity
GO:0051149 TAS positive regulation of muscle cell differentiation
GO:0051403 TAS stress-activated MAPK cascade

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000088823 Mapk11-201 protein_coding Mus_musculus 0 1358
ENSMUST00000062694 Mapk14-002 protein_coding Mus_musculus 0 414
ENSMUST00000004990 Mapk14-001 protein_coding Mus_musculus 0 405
ENSMUST00000114758 Mapk14-004 protein_coding Mus_musculus 0 405
ENSMUST00000114752 Mapk14-005 protein_coding Mus_musculus 0 381
ENSMUST00000114754 Mapk14-003 protein_coding Mus_musculus 0 381

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