C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: preferentially expressed antigen in melanoma
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000185686 PRAME 9606 - 22:22547701-22559361 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000398741 PRAME-201 22547702-22559143 protein_coding
  ENST00000398743 PRAME-001 22547701-22559340 protein_coding
  ENST00000402697 PRAME-003 22547767-22559288 protein_coding
  ENST00000403441 PRAME-009 22550852-22557754 protein_coding
  ENST00000405655 PRAME-004 22547704-22559143 protein_coding
  ENST00000406503 PRAME-006 22550754-22559267 protein_coding
  ENST00000420709 PRAME-008 22550221-22559083 protein_coding
  ENST00000438888 PRAME-012 22550183-22555926 protein_coding
  ENST00000439106 PRAME-005 22550074-22559279 protein_coding
  ENST00000442481 PRAME-011 22550819-22557592 nonsense_mediated_decay
  ENST00000476336 PRAME-010 22550246-22557721 processed_transcript
  ENST00000485532 PRAME-013 22550299-22554179 processed_transcript
  ENST00000492657 PRAME-002 22547701-22559361 retained_intron
  ENST00000543184 PRAME-202 22547702-22559289 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeBrainBreastColonKidneyLungOvaryPlacentaTestisENST00000398743ENST00000402697ENST00000403441ENST00000405655ENST00000406503ENST00000442481ENST00000476336ENST00000543184
Transcript ID Adipose Brain Breast Colon Kidney Lung Ovary Placenta Testis
ENST00000398743 N/A N/A N/A N/A N/A N/A 2.265±0.00 0.046±0.00 18.673±1.07
ENST00000402697 0.066±0.00 N/A 0.027±0.00 0.059±0.00 0.301±0.00 0.032±0.00 2.180±0.41 1.780±0.00 N/A
ENST00000403441 N/A N/A N/A 0.113±0.00 N/A N/A N/A N/A N/A
ENST00000405655 N/A 0.042±0.00 N/A N/A N/A N/A 1.031±0.00 0.046±0.00 29.831±0.00
ENST00000406503 N/A 0.197±0.00 N/A N/A N/A N/A N/A N/A N/A
ENST00000442481 N/A N/A N/A N/A N/A N/A 1.066±0.00 N/A N/A
ENST00000476336 0.184±0.00 N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000543184 N/A N/A N/A N/A N/A N/A 1.023±0.54 N/A 13.859±0.00

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005515 IPI protein binding
GO:0005634 IEA nucleus
GO:0005886 IEA plasma membrane
GO:0006351 IEA transcription, DNA-templated
GO:0006915 IEA apoptotic process
GO:0008284 IDA positive regulation of cell proliferation
GO:0030154 IEA cell differentiation
GO:0040008 IEA regulation of growth
GO:0042974 IDA retinoic acid receptor binding
GO:0043066 IDA negative regulation of apoptotic process
GO:0045596 IDA negative regulation of cell differentiation
GO:0045892 IDA negative regulation of transcription, DNA-templated
GO:0048387 IDA negative regulation of retinoic acid receptor signaling pathway

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000036493 PRAMEF1 PRAME family member 1 protein_coding Danio_rerio

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