C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: neuregulin 3
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000185737 NRG3 9606 + 10:81875314-82987179 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000372141 NRG3-004 81875314-82985645 protein_coding
  ENST00000372142 NRG3-001 81877687-82986967 protein_coding
  ENST00000404547 NRG3-005 81875341-82985605 protein_coding
  ENST00000404576 NRG3-003 81877961-82985605 protein_coding
  ENST00000537893 NRG3-201 82799742-82985605 protein_coding
  ENST00000545131 NRG3-202 82738576-82987179 protein_coding
  ENST00000555784 NRG3-006 81877961-82985605 nonsense_mediated_decay
  ENST00000556918 NRG3-002 81877961-82985605 protein_coding
  ENST00000602794 NRG3-007 81877897-82987179 nonsense_mediated_decay

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeBladderBrainBreastColonHeartKidneyLiverLungOvaryPlacentaTestisENST00000372141ENST00000404547ENST00000404576ENST00000537893ENST00000545131ENST00000602794
Transcript ID Adipose Bladder Brain Breast Colon Heart Kidney Liver Lung Ovary Placenta Testis
ENST00000372141 0.008±0.00 N/A 3.108±1.19 0.018±0.00 0.061±0.00 0.040±0.00 N/A 0.105±0.00 0.572±0.00 0.087±0.07 0.031±0.00 N/A
ENST00000404547 N/A N/A 1.846±0.00 N/A N/A N/A N/A N/A 0.171±0.00 N/A 0.147±0.00 0.175±0.00
ENST00000404576 N/A 0.313±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000537893 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.029±0.00 0.251±0.00
ENST00000545131 0.013±0.00 N/A 4.690±1.20 0.020±0.00 N/A 0.030±0.00 0.174±0.04 0.063±0.00 N/A 0.060±0.00 0.052±0.03 N/A
ENST00000602794 N/A 0.054±0.00 N/A N/A N/A N/A 0.085±0.00 N/A 0.076±0.00 N/A N/A 0.063±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0005NZ CIL_0005NZ_0002 CGP 10:80537902-82987179

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001558 NAS regulation of cell growth
GO:0005102 IEA receptor binding
GO:0005515 IEA protein binding
GO:0005576 NAS extracellular region
GO:0005887 NAS integral component of plasma membrane
GO:0007171 NAS activation of transmembrane receptor protein tyrosine kinase activity
GO:0007389 IEA pattern specification process
GO:0008083 NAS growth factor activity
GO:0009790 IEA embryo development
GO:0030297 NAS transmembrane receptor protein tyrosine kinase activator activity
GO:0030879 IEA mammary gland development
GO:0030971 NAS receptor tyrosine kinase binding
GO:0035556 IEA intracellular signal transduction
GO:0060596 IEA mammary placode formation

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000089766 si:dkey-17e6.2 neuregulin 3 protein_coding Danio_rerio
ENSMUSG00000041014 Nrg3 neuregulin 3 protein_coding Mus_musculus

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