C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: G protein-coupled receptor kinase 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000185974 GRK1 9606 + 13:113667155-113737735 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000335678 GRK1-001 113667155-113737735 protein_coding
  ENST00000545304 GRK1-003 113726486-113735236 processed_transcript
  ENST00000606140 GRK1-002 113734475-113737735 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdrenalBrainHeartKidneyLungOvaryTestisENST00000335678ENST00000545304ENST00000606140
Transcript ID Adrenal Brain Heart Kidney Lung Ovary Testis
ENST00000335678 N/A N/A N/A N/A N/A N/A 0.081±0.02
ENST00000545304 N/A N/A 0.042±0.00 N/A N/A N/A N/A
ENST00000606140 0.030±0.00 0.074±0.00 0.036±0.00 0.040±0.00 0.008±0.00 0.055±0.00 0.046±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0000SN CIL_0000SN_0001 CGP 13:113648804-113737735
CIL_0000SF CIL_0000SF_0001 CGP 13:113667155-113816995

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004672 TAS:IEA protein kinase activity
GO:0004674 IEA protein serine/threonine kinase activity
GO:0004703 IEA G-protein coupled receptor kinase activity
GO:0004713 IEA protein tyrosine kinase activity
GO:0005524 IEA ATP binding
GO:0006468 IEA protein phosphorylation
GO:0007601 IEA visual perception
GO:0007603 TAS phototransduction, visible light
GO:0008277 TAS:IEA regulation of G-protein coupled receptor protein signaling pathway
GO:0008594 IEA photoreceptor cell morphogenesis
GO:0009416 IEA response to light stimulus
GO:0016056 TAS rhodopsin mediated signaling pathway
GO:0016772 IEA transferase activity, transferring phosphorus-containing groups
GO:0022400 IDA regulation of rhodopsin mediated signaling pathway
GO:0038032 IEA termination of G-protein coupled receptor signaling pathway
GO:0042327 IEA positive regulation of phosphorylation
GO:0043066 IEA negative regulation of apoptotic process
GO:0046777 IMP protein autophosphorylation
GO:0050254 IDA rhodopsin kinase activity
GO:0060060 IEA post-embryonic retina morphogenesis in camera-type eye
GO:0097381 TAS photoreceptor disc membrane

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000058803 grk1a G protein-coupled receptor kinase 1 a protein_coding Danio_rerio
ENSMUSG00000031450 Grk1 G protein-coupled receptor kinase 1 protein_coding Mus_musculus

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